نتایج جستجو برای: insulin nanoparticles
تعداد نتایج: 289894 فیلتر نتایج به سال:
the application of low-frequency ultrasound for transdermal delivery of insulin is of particular public interest due to the increasing problem of diabetes. the purpose of this research was to develop an air ultrasonic ceramic transducer for transdermal insulin delivery and evaluate the possibility of applying a new portable and low-cost device for transdermal insulin delivery. twenty-four rats ...
objective: social belief and experimental evidences indicate that opium and its alkaloids, morphine, produced hypoglycemic effects in animal models. this study was conducted in order to determine the role of morphine on blood glucose and insulin. material and methods: this is an empirical analysis investigating the laboratory albino male rats weighing 200-250 g. rats in the control group receiv...
Background: All contemporary methods of insulin administration are non-physiological. Insulin is not absorbed from the gastrointestinal tract because of its peptide nature. The aim of the present study was to examine the absorption of oral insulin from gastrointestinal tract, using novel oral formulation- adding a delivery agent superporouse hydrogel (SPH) and SPH composite (SPHC) in combinat...
Background: Patients with type 2 diabetes are often obese and require large dose of insulin to achieve glycemic control. Insulin therapy often cause weight gain and results in increasing insulin requirements. This study was conducted to evaluate the efficacy of metformin in combination with insulin in patients with type 2 diabetes poorly controlled with insulin therapy alone. Materials and Meth...
abstract: camel milk contains sufficient levels of insulin and does not form the coagulum in the stomach preventing degradation of insulin and act as an effective vehicle to take the milk insulin unchanged to the intestine. in present study direct spectroscopy and standard addition method, well-known methods in analytical chemistry were used for determining insulin concentration in camel milk. ...
background: polycystic ovarian syndrome (pcos) is a common disease among women in fertility ages and cause severe insulin resistance. hyperhomocysteinaemia is said to be among the features of pcos that could influence its outcome. objective: this study aimed to investigate whether hyperhomocysteinaemia exists in pcos and if it is related to insulin resistance in the affected patients. materials...
conclusions it appears that fenugreek seed might be effective against hyperglycemia, hyperlipidemia and insulin resistance in ovariectomized rats without impact on serum apelin. furthermore, 17-β estradiol could have similar effects along with possible inhibitory effects on serum apelin. the complicated role of apelin in menopause needs to be further explored. results serum apelin, glucose, lip...
Background: Glucokinase serves as a glucose sensor in pancreatic β-cells and plays a key role in glucose homeostasis and glucose-stimulated insulin secretion (GSIS). In the present study we examined the effect of glucosamine, a glucokinase inhibitor, on the pancreatic glucokinase and hexokinase activities and on insulin secretion from freshly rat pancreatic islets of Langerhans. Insulin concen...
inhalational insulin was withdrawn from the market due to its potential to produce airway hyper-reactivity and bronchoconstriction. so the present study was designed to explore the acute effects of insulin on airway reactivity of guinea pigs and protective effects of salbutamol and ipratropium against insulin induced airway hyper-responsiveness on isolated tracheal smooth muscle of guinea pig. ...
Background: Visfatin is an adipokine secreted from visceral adipose tissue and involved in glucose homeostasis. The aim of the present study was to investigate the effect of eight-week resistance training on plasma visfatin levels and its relation to insulin resistance in insulin-resistant male rats. Methods: In this experimental study twenty-four Wistar male rats (220±20 gr) were acclimati...
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