1210. A Phase 3, Randomized, Double-Blind, Non-inferiority Trial to Evaluate Efficacy and Safety of Isavuconazole versus Voriconazole in Patients with Invasive Mold Disease (SECURE): Outcomes in Neutropenic Patients Thomas Patterson,; Dominik Selleslag,; Kathleen Mullane,; Oliver Cornely,; William Hope,; Olivier Lortholary,; Bernhardt Zeiher,; Rochelle Maher,; Misun Lee,; Wenmei Huang,; Dimitri...

DOMINIQUE GAILLARD,1 JOCELYNE HINNRASKY,1 SYLVIE COSCOY,2 PAUL HOFMAN,3 MICHAEL A. MATTHAY,4 EDITH PUCHELLE,1 AND PASCAL BARBRY2,4 1Institut National de la Santé et de la Recherche Médicale Unité 514, Institut Fédératif de Recherches 53, Centre Hospitalier Universitaire Maison Blanche, 51092 Reims Cedex; 2Institut de Pharmacologie Moléculaire et Cellulaire, Centre National de la Recherche Scien...

Chemistry Aware Model Builder Isidro Cortes-Ciriano∗1,5, Daniel S. Murrell†2,5, Gerard J. P. van Westen, Ian P. Stott, Andreas Bender, Therese E. Malliavin, and Robert C. Glen Unite de Bioinformatique Structurale, Institut Pasteur and CNRS UMR 3825, Structural Biology and Chemistry Department, 25-28, rue Dr. Roux, 75 724 Paris, France. Unilever Centre for Molecular Science Informatics, Departme...

1Center for Infection and Immunity of Lille (CIIL), INSERM U1019 – CNRS UMR 8204, Institut Pasteur de Lille, Université Lille Nord de France, Lille, France, 2Faculty of Veterinary Medicine, University of Zaragoza, Zaragoza, Spain, 3Biology Centre, Institute of Parasitology, The Czech Academy of Sciences, České Budějovice, Czech Republic, 4Department of Virology, Veterinary Research Institute, B...

The Fogarty International Center at NIH has the mission of supporting training and research in global health with a focus on problems in low and middle income countries. Our programs provide research opportunities in both infectious and chronic diseases that link investigators and institutions in the United States with groups in the developing world. The value of these long term investments is ...

R. A. Molina,1,2 A. P. Zuker,3 A. Relaño,4 and J. Retamosa4 1Commissariat a l’Energie Atomique, Service de Physique de l’Etat Condensé, F-91191 Gif-sur-Yvette, France 2Max-Planck-institut für Physik Komplexer Systeme, Nöthnitzer Strasse 38, D-01187 Dresden, Germany 3IReS, Bât27, IN2P3-Centre National de la Recherche Scientifique/Université Louis Pasteur BP 28, F-67037 Strasbourg Cedex 2, France...

Daniel S. Murrell∗1,5, Isidro Cortes-Ciriano†2,5, Gerard J. P. van Westen, Ian P. Stott, Andreas Bender, Therese E. Malliavin, and Robert C. Glen Unilever Centre for Molecular Science Informatics, Department of Chemistry, University of Cambridge, Cambridge, United Kingdom. Unite de Bioinformatique Structurale, Institut Pasteur and CNRS UMR 3825, Structural Biology and Chemistry Department, 25-2...

ISOPOL - for "International Symposium on Problems of Listeria and Listeriosis" - meetings gather every three years since 1957 participants from all over the world and allow exchange and update on a wide array of topics concerning Listeria and listeriosis, ranging from epidemiology, diagnostic and typing methods, to genomics, post-genomics, fundamental microbiology, cell biology and pathogenesis...

Despite the promising paradigm offered by high-content screening, the concrete execution of hundred of thousands of visual cell-based experiments has remained highly challenging in terms of both statistical robustness and speed. An efficient computational method for cellular microarrays was developed at Institut Pasteur-Korea that allow for high speed, high content genome-wide siRNA screening. ...

Waleed Mazi, Vartul Sangal, Amir Saeed, Gunnar Sandstrom, François-Xavier Weill, Jun Yu Karolinska Institute, Department of Laboratory Medicine, Division of Clinical Microbiology, Karolinska University Hospital, Huddinge, Stockholm, Sweden; Strathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, Strathclyde, United Kingdom; Faculty of Health and Life Sciences, Nort...