Inherited and Secondary Thrombophilia Print ISSN: 0009-7322. Online ISSN: 1524-4539 Copyright © 2014 American Heart Association, Inc. All rights reserved. is published by the American Heart Association, 7272 Greenville Avenue, Dallas, TX 75231 Circulation doi: 10.1161/CIRCULATIONAHA.113.001943 2014;129:254-257 Circulation. http://circ.ahajournals.org/content/129/2/254 World Wide Web at: The onl...

Two experiments provide evidence that our conceptual systems represent hierarchical relations between concepts in more than one way. Specifically, hierarchical relations may be represented via criteria inclusion or kind specification. The experiments provide the first evidence that these two ways of representing hierarchical relations mediate feature inheritance in systematically different ways...

Inherited cardiac arrhythmia syndromes have received a lot of attention in recent years, particularly the molecular genetic basis, which has been unraveled to a great extent in the past years. Disease entities have been subdivided based on their causal gene defect, which, indeed, has been shown to impact on disease expression, clinical characteristics, prognosis and treatment. This particularly...

Lethal cardiac arrhythmias in individuals with structurally normal heart are often caused by variants in genes that encode cardiac ion channel and -subunits (102). Common inherited arrhythmia syndromes include the congenital long QT syndrome (LQTS), Brugada syndrome (BrS), short QT syndrome (SQT), and catecholaminergic polymorphic ventricular tachycardia (CPVT) (76). Moreover, inherited mutatio...

I am usually highly resistant to exhortations from reviewers that a particular book is 'essential reading'. But now and again one appears which should command our attention and I urge all paediatricians to read Penelope Leach's new book. Her case is that 'post-industrial western societies', such as the UK, ignore or override the special needs of children to such an extent that they miss out and...