This book is a distillation of the authors' experience with human infertility-its prevalence, implications, diagnosis, and treatment. It is a useful practical guide for the physician who deals with this problem and includes detailed discussion of the techniques of investigation. There is an excellent chapter on endometrial interpretation by the late Dr. Earle T. Engle. The authors are to be com...

Approximately 8-10% of couples are facing some kind infertility problem. Infertility is defined as a couple's inability to achieve pregnancy over an average one year without using birth control methods and while engaging in normal sexual intercourse. Primary secondary the two types infertility. The high percentage female reproductive age factors influencing infertility, well existing studies on...

Female infertility was reported to account for about 55% of cases, male factor accounted 30% 40% cases and unexplained the remaining 5 percent 15 cases. In Africa, infections resulting in tubo-peritoneal oligo-azoospermia (low sperm count) are most common causes infertility. Infertility is widespread Sub-Saharan Africa ranging from 13–17 countries with pockets high prevalence at 32%. The genera...

Balanced reciprocal translocations are associated with reproductive failure. Some reciprocal translocation carriers exhibit azoospermia or oligozoospermia, and an association exists between these chromosomal abnormalities and recurrent abortion. Previous reports have indicated the involvement of chromosome 7 translocations in male infertility and recurrent miscarriage. A translocation breakpoin...

The misconception that infertility is typically associated with the female is commonly faced in the management of infertile men. It is uncommon for a patient to present for an infertility evaluation with an abnormal semen analysis report before an extensive female partner workup has been performed. Additionally, a man is usually considered fertile based only on seminal parameters without a phys...

Factors affecting the blood-testis barrier function may be involved in testicular damage and male infertility. Two cytokines play an important role in the barrier regulation, namely transforming growth factor beta 3 (TGF-β3) and tumor necrosis factor (TNF-α). The aim of this study was to investigate the potential association between TGF-β3 (TGFB3) and TNF-α (TNF) gene polymorphisms and male inf...

Description: Infertility is usually a consequence of multiple chronic conditions rather than a single acute condition. We propose that it is erroneous to apply acute medical interventions to a condition that is chronic in nature. Method: Retrospective analysis of 3 case studies which demonstrate the multifactorial and chronic nature of infertility that were previously managed unsuccessfully wit...

OBJECTIVE To determine whether nucleolar channel systems (NCSs) in the midluteal endometrium are associated with overall fertility status and/or with unexplained infertility. DESIGN Retrospective and prospective clinical studies. SETTING Repository of stored specimens from prior multicenter study and private infertility center. PATIENT(S) Retrospective study that included 97 women (49 fer...

Infertility is a private, social, and economic problem. Infertility is defined as the inability to conceive a pregnancy within 1 year. Twenty-five percent of couples will seek help for infertility at some point during their relationship (Page, 1989), accounting for over 2 million office visits to health care providers annually (The Endocrine Society, 1998). Male factor infertility is contributo...

Introduction: When planning infertility services in sub-Saharan Africa (SSA) the management of HIV infected couples needs careful attention. Very little is known about the potential demand for infertility services among HIV infected couples, the interplay between HIV infection and infertility and the specific counselling needs of this group. Methods: A review of the literature was combined with...