Introduction Atresias of the jejunum and ileum are common causes of bowel obstruction in the neonate, with a third of infants born prematurely or small for their gestational age. Stenoses are much less common and seldom present in the newborn period due to delay in diagnosis. Whereas these conditions are associated with excellent prognoses in developed countries, delayed presentation and limita...

The chest X-ray is the most valuable imaging modality in the assessment of the neonate with respiratory distress. Whilst many of the radiological appearances are relatively non-specific, integration of the clinical features with the X-ray appearances will help the clinician arrive at the correct diagnosis in most cases. In a minority of infants, particularly those with a congenital malformation...

Spontaneous gallbladder perforation among the pediatric population is a rare occurrence. To date only 8 cases have been described in the English literature in neonates and infants [1-8]. Presenting signs and symptoms vary, as do treatment methodologies. Patients have presented with bilious drainage from peritoneal catheters [1] abdominal distention with discoloration [2] discolored communicatin...

Symptomatic cytomegalovirus (CMV) infection mainly affects preterm and immunocompromised infants and usually manifest as rash, pneumonia, hepatospleenomegaly or encephalitis. To our knowledge intractable diarrhoea at two weeks of age caused by postnatally acquired CMV in immunocompetent term neonate is not reported. An unusual case of postnatally acquired CMV enterocolitis manifesting as protra...

The discovery of cholelithiasis in neonates is often incidental, however obstructing common bile duct stones are rare. Herein we report the case of a 3 week old neonate who presented with obstructive choledocholithiasis. The patient was treated conservatively with antibiotics and ursodeoxycholic acid but did not improve. He was therefore taken to surgery for cholecystectomy and stone extraction...

Introduction: some studies have suggested correlation between MPV index and inflammatory diseases such as rheumatoid arthritis in adults. Though bronchopulmonary dysplasia is also an inflammatory disease which develops in preterm neonates with Respiratory distress syndrome, we decided to study the possible correlation between the mean platelet volume (MPV) and the occurrence of bronchopulmonary...

Abstract Background Antenatal and neonatal viral exposure may put the developing brain at risk for abnormal neurodevelopment. A clinical follow-up program was created in Congenital Infection Program Children’s National Hospital to follow infants with utero or early life SARS-CoV-2. The aim of this study determine if SARS-CoV-2 have neurodevelopment infancy. Methods We performed a retrospective ...

An analysis was done of available data from the Department of Statistics Malaysia, on the type of congenital abnormality contributing to death, to determine whether progress in health care over recent years was associated with any decline in mortality from congenital abnormality. A significant decline in death due to congenital abnormality was observed between 1991 and 1996. This was attributab...

Central venous catheters are widely used in children, particularly in very-low-birth-weight infants in whom long-term access to the venous system is required. This may be achieved by using peripherally inserted central catheters or tunnelled central venous lines (eg Broviac or Hickman lines). Previous case reports of fractured central catheters in premature neonates have involved peripherally i...

OBJECTIVES/HYPOTHESIS We describe management of an infant with chronic aspiration as a result of severe and rarely described laryngeal dysgenesis. RESULTS A neonate with severe maldevelopment of the laryngeal structures required tracheostomy for respiratory distress on day-of-life 1, but the patient continued to have aspiration pneumonias. After failing to improve with conservative measures, ...