Orexinergic system may play an important role in the regulation of anesthesia-arousal. However, which region or which pathway mediated the effect of orexins was still unclear. In current study, we investigated whether activation of orexin signals in basal forebrain (BF) may alter electroencephalographic activity, induction and emergence time to sevoflurane anesthesia in rats. Either orexin-A or...

OBJECTIVE To compare the hypnotic effects (using Bispectral Index [BIS]), hemodynamic parameters, injection pain and quality of anesthesia during induction of anesthesia of the 3 commercial propofol preparations (Abbott Propofol, Abbott Laboratories), Pofol (Dongkook Pharm. Co. Ltd.), and Propofol 1% Fresenius (Fresenius Kabi). METHODS After Ethics Committee Approval, a prospective, randomize...

BACKGROUND This study was performed to compare the incidence of emergence agitation (EA) between inhalation and intravenous anesthesia induction in children after sevoflurane anesthesia. METHODS In this prospective and double-blind study, 100 children aged 3 to 7 years were enrolled. Subjects were randomly assigned to the sevoflurane (Group S) or thiopental (Group T) anesthesia induction grou...

normal 0 false false false en-us x-none ar-sa microsoftinternetexplorer4 background : it has been shown that bispectral index (bis) may reduce during spinal anesthesia. the aim of this study was comparing bis scores during spinal anesthesia using hyperbaric bupivacaine alone or with intrathecal or intravenous fentanyl for cesarean section. methods : in this double-blind randomized controlled cl...

hemodynamic changes are major hazards of general anesthesia and are probably generated by direct laryngoscopy and endotracheal intubation. we designed this prospective randomised study to assess the cardiovascular changes after either laryngeal mask airway (lma), face mask (fm) or endotracheal tube (ett) insertion in the airway management of adult patients anesthetised with nitrous oxide and ha...

Objective: To compare the effect of sevoflurane and total intravenous anesthesia (TIVA) on anesthesia induction, maintenance and postoperative recovery in patients receiving cardiac surgeries. Methods: Overall, 80 patients admitted in our hospital to receive cardiac surgery between January 2015 and January 2017 were enrolled in our study. They were randomized into the sevoflurane anesthesia (SA...

RATIONALE Coffin-Lowry syndrome (CLS) is a rare inherited disease with specific clinical features, such as mental retardation, facial dysmorphism, and cardiac abnormality. In particular, the characteristic facial features of CLS, including retrognathia and large tongue, are associated with difficult ventilation and/or intubation, which is a serious problem of anesthesia management. However, cas...

BACKGROUND Thiopental and propofol have been widely used for general anesthesia induction, but their impacts on cardiac function have not been well described. A recent study speculated that anesthesia induction using propofol 2 mg/kg transiently reduced left ventricular (LV) contraction by analyzing tissue Doppler-derived imaging (TDI) during induction phase. The purpose of this study was to an...