Hypercholesterolemia is well established as a major risk marker for atherosclerosis and resultant cardiovascular disease. Recent studies suggest that platelets are intimately involved not only in thrombosis after plaque rupture, but also in the earliest events in the atherogenic process.1 In this issue of Arteriosclerosis, Thrombosis, and Vascular Biology, Tailor and Granger2 establish another ...

During the prevailing coronavirus disease 2019 (COVID-19) pandemic, has started manifesting with some neurological symptoms. There have been reports on acute ischemic stroke, cerebral venous thrombosis, and intracerebral hemorrhage associated COVID-19. The plausible mechanism that causes these processes is called sepsis-induced coagulopathy. A 40-year male patient, who was hospitalised due to C...

The distribution, severity, and complications of diet-induced atherosclerosis in dogs can be altered by changing the source of fat in the diet. Thrombosis and thromboembolic disease associated with atherosclerosis occurred with diets containing beef tallow and lard of coconut oil but were absent in dogs fed cottonseed oil as a source of fat. Experiemtnal animals with and without thrombosis are ...

Patients with grade IV or V renal injury frequently have associated visceral injuries that can limit options such as open surgical repair or anticoagulation. The use of endovascular stents to treat trauma-induced renal artery thrombosis and intimal damage appears promising. However, data verifying the effectiveness of the treatment is lacking. We present a case of acute renal artery revasculari...

We report findings of magnetic resonance imaging including susceptibility-weighted imaging (SWI) of the subacute torsion of an ovarian fibrothecoma in a patient with renal dysfunction. Although venous thrombosis within the vascular pedicle mimicked a malignant tumor, showing high signal intensity on T2-weighted images and diffusion-weighted imaging, we diagnosed ovarian torsion on SWI without t...

background: the purpose of this study is to demonstrate the advantages of gradient echo (gre) sequences in the detection and characterization of cerebral venous sinus thrombosis compared to conventional magnetic resonance sequences. methods: a total of 17 patients with cerebral venous thrombosis (cvt) were evaluated using different magnetic resonance imaging (mri) sequences. the mri sequences i...

conclusions in our population of cirrhotic patients, treatment of variceal bleeding predisposed the patients to portal vein thrombosis, but hypercoagulable disorders by themselves were not associated with portal vein thrombosis. results there was no statistically significant difference in the assessed hypercoagulable states between patients with or without portal vein thrombosis. a history of p...

Prothrombotic fibrin clot phenotype, involving faster formation of dense meshwork composed of thinner and highly branched fibers that are relatively resistant to plasmin-induced lysis, has been reported in patients with not only myocardial infarction or stroke, but also venous thromboembolism (VTE), encompassing deep vein thrombosis (DVT), and/or pulmonary embolism (PE). Prothrombotic fibrin cl...

BACKGROUND Cerebral venous thrombosis is a rare complication of polycythemia. To our knowledge, epoetin alfa-induced polycythemia has not previously been reported in association with cerebral venous thrombosis. CASE DESCRIPTION A 37-year-old patient who was receiving peritoneal dialysis and epoetin alfa (Epogen) therapy presented with a several-day history of worsening headache, and a neuroim...

Shear induced platelet activation is responsible for arterial thrombosis. The role of fibrinogen is established at low shear stress, but at high shear stress von Willebrand factor (vWF), not fibrinogen, is essential for platelet adhesion and aggregation. Patients with vWF deficiency exhibit resistance to thrombosis, and raised vWF is a risk factor for acute coronary syndromes. Interpretation of...