As a first step in investigating the role of retinoic acid (RA) in mouse testis, we analyzed the distribution pattern of the enzymes involved in vitamin A storage (lecithin:retinol acyltransferase), RA synthesis (beta-carotene 15,15'-monoxygenase and retinaldehyde dehydrogenases) and RA degradation (cytochrome P450 hydroxylases) as well as those of all isotypes of receptors transducing the RA s...

P450 aromatase is a key enzyme in steroidogenesis involved in the conversion of testosterone into 17β-estradiol. We investigated the localization and the expression of P450 aromatase in Podarcis sicula testes during the different phases of the reproductive cycle: summer stasis (July-August), early autumnal resumption (September), middle autumnal resumption (October-November), winter stasis (Dec...

in this study, the effects cold rolling and annealing parameters during thermomechanical processing of the aisi 201ln stainless steel were investigated. the cast samples were homogenized, hot-rolled and solution-annealed to acquire a suitable microstructure for the subsequent thermomechanical treatment. unidirectional and transverse multi-pass cold rolling at 25, 0 and -15 °c was carried out to...

background: radiation-induced discomfort is frequently observed during pelvic radiotherapy. this study was performed to determine the effect of a green tea tablet to reduce the incidence of radiation-induced diarrhea and vomiting in patients with abdomen and pelvic malignancy. materials and methods: this randomized controlled clinical trial recruited 42 patients with abdomen and pelvic malignan...

background:the pattern of poisoning has a regional variability. this study was carried out to describe the epidemiological profile of acute poisoning in northeastern bangladesh and to evaluate the mortality. methods:in this retrospective cross-sectional study, medical records of poisoned patients treated at department of medicine of sylhet m.a.g. osmani medical college hospital, sylhet, banglad...

the harmful use of alcohol causes an estimated 2.5 million deaths every year, of which a significant proportion occur in the young. alcohol use is the third leading risk factor for poor health globally. in response to harmful use of alcohol, world health organization developed a global strategy to reduce the harmful use of alcohol endorsed by the sixty-third world health assembly in 2010. paral...

background: bladder cancer (bc) is the most common genitourinary cancer in iranians with an unclear etiopathogenesis. long stress induced non-coding transcript 5 is a member of the 12-member family of long non-coding rnas, which is abundantly expressed in higher proliferative cells, as well as the cell vulnerable to cellular stress in response to chemical carcinogens. as variations in long non-...

this research intends to develop a method based on the artificial neural network (ann) to predict permanent earthquake-induced deformation of the earth dams and embankments. for this purpose, data sets of observations from 152 published case histories on the performance of the earth dams and embankments, during the past earthquakes, was used. in order to predict earthquake-induced deformation o...