The journal retracts the following article: “Efficacy of Mesenchymal Stem Cell and Vitamin D in Treatment Diabetes Mellitus Induced a Rat Model: Pancreatic Tissues [...]

OBJECTIVE Stress induced hyperglycemia occurs in critically ill patients who have normal glucose tolerance following resolution of their acute illness. The objective was to evaluate the association between stress induced hyperglycemia and incident diabetes in survivors of critical illness. DESIGN Retrospective cohort study. SETTING All adult patients surviving admission to a public hospital...

interleukin-1β (il-1β) has a role in β- cell destruction in autoimmune diabetes by stimulating the expression of inducible nitric oxide synthase (inos) that generates the free radical nitric oxide. we aimed to investigate the effect of achillea millefolium l, as a traditional hypoglycemic agent, on il-1β and inos gene expression of pancreatic tissue in the stz- induced diabetic rats. forty adul...

Abstract Diabetes mellitus (DM) is a set of metabolic diseases defined by persistently high blood sugar level. Mesenchymal stem cells (MSCs) are novel potential therapeutic intervention in treatments various diseases, which also referred to as regenerative medicine. We aimed compare the pro-inflammatory cytokines’ levels during bone marrow mesenchymal (BM-MSCs) transplantation rats with induced...

Background: Clinical evidence points to the effective role of genetic factors and intracellular signaling pathways in physiological cardiac hypertrophy. This study aimed to assess the response of PI3K/mTORc1 signaling pathway in cardiac tissue to resistance training in obese diabetic rats. Materials and Methods: For this purpose, 21 male wistar rats (220±20 g) were obese by 6 weeks high fat di...

Increasing the level of urea and uric acid is an associated complication of diabetes mellitus. Many spices and herbs are known to be hypoglycaemic. Olea europaea belonging to the family oleaceae is widely used in herbal medicine for the treatment of diabetes. The present study was carried out to investigate the role of the alcoholic extract from leaves of olive on level of urea and uric acid in...

objective: diabetes is an important risk factor for cardiovascular events. the great percent of morbidity in patients with diabetes is due to endothelial dysfunction. the present study investigated the effects of hydroalcholic extract of nigella sativa (n. sativa)  on contractile and dilatation response of isolated aorta in streptozotocin (stz)-induced diabetic rat. materials and methods: rats ...

the effects of chronic metabolic acidosis, alkalosis and alloxan-induced ketoacidosis on g6pd activity of rat kidney, liver and erythrocytes were studied. metabolic acidosis significantly increased the activity of kidney enzyme (55%) but decreased the liver (43%) and erythrocyte (38%) enzyme activities. alkalosis did not make a significant change in the kidney or liver enzyme activity but sligh...