BACKGROUND Floor dust is commonly used for microbial determinations in epidemiological studies to estimate early-life indoor microbial exposures. Resuspension of floor dust and its impact on infant microbial exposure is, however, little explored. The aim of our study was to investigate how floor dust resuspension induced by an infant's crawling motion and an adult walking affects infant inhalat...

We examined associations between reported home characteristics and levels of indoor allergens in 499 homes of a birth cohort of children of allergic/asthmatic families from the Boston area. The risk of having dust mite allergen (Der f 1 or Der p 1) > or = 2 microg/g on the bedroom floor was highest in houses, but 16% of apartments had levels this high. Compared with that from smooth floors, dus...

Studies of indoor allergen exposures are often limited by the cost and logistics of sending technicians to homes to collect dust. In this study we evaluated the feasibility of having subjects collect their own dust samples. The objectives were to compare allergen concentrations between subject- and technician-collected samples and to examine the sample return rate. Using a dust collection devic...

Histamine is used in bronchial and dermal provocation, but it is rarely considered an environmental risk factor in allergic disease. Because bed bugs defecate large amounts of histamine as a component of their aggregation pheromone, we sought to determine if histamine accumulates in household dust in bed bug infested homes, and the effects of bed bug eradication with spatial heat on histamine l...

Management of asthma requires attention to environmental exposures both indoors and outdoors. Americans spend most of their time indoors, where they have a greater ability to modify their environment. The indoor environment contains both pollutants (eg, particulate matter, nitrogen dioxide, secondhand smoke, and ozone) and allergens from furred pets, dust mites, cockroaches, rodents, and molds....

Once an aerosol contaminant is introduced into an indoor environment, it can remain in the air, deposit on interior surfaces or attach to dust particles already present. Human activity, such as walking and cleaning, resuspends contaminated particles, regenerating airborne contaminants. This report is a literature review on the effects of human activity on particle re-suspension in indoor enviro...

Background: Epidemiologic studies have demonstrated an association between indoor fungal growth and respiratory symptoms. However, in only a few studies was fungal exposure actually measured. Objective: The purpose of this study was to evaluate the measurement by enzyme immunoassay of extracellular polysaccharides of Aspergillus and Penicillium species (EPS-Asp/Pen) in house dust as a marker fo...

“Comparison of the Inflammatory Potency of Bacteria in Their Cell Wall Components in theLung.” JM Gassman, PS Thorne, M O’Neill, J Phipps, K Kulhankova, C Duchaine, Toxicological Sciences,The Toxicologist, March 2000, 39 Annual Meeting Society of Toxicology. March 2000. Abstract: “A National Survey of Endotoxin in House Dust”, PS Thorne, K Kulhankova, M. O’Neill, PJVojta, W Friedman...