The United States has a trust responsibility to provide services to American Indians and Alaska Native (AI/AN) persons. However, a long-standing history of underfunding of the Indian Health Service (IHS) has led to significant challenges in providing services. Twentieth century laws, including the Snyder Act, Transfer Act, Indian Self-Determination and Education Assistance Act, and Indian Healt...

A possible link between melanization and desiccation resistance can be inferred if within population differences in melanization find significant correlations with desiccation resistance and its mechanistic basis i.e. rate of water loss/hr. Accordingly, darker, intermediate and lighter phenotypes of body melanization were analyzed in wild and laboratory reared Drosophila melanogaster L. (Dipter...

The colonial category of mestizo was an ideological tool that shaped national identity in the post-revolutionary period in Mexico. The Indian-mestizo axis functioned to organize the ethnic and political interactions of the state. Doctors and anthropologists reinforced this dual taxonomy in studies of human populations, using biomedical markers to produce differentiated descriptions of the India...

BACKGROUND Differences in level of physical activity between European, Indian, Pakistani and Bangladeshi populations living in the UK might contribute to differences in the prevalence of diabetes and cardiovascular disease risk markers that exist in these populations. METHODS Type and level of physical activity (measured by a multidimensional index) and its relationship with selected cardiova...

APOBEC3B, a gene involved in innate response, exhibits insertion-deletion polymorphism across world populations. We observed the insertion allele to be nearly fixed in malaria endemic regions of sub-Saharan Africa as well as populations with high malaria incidence in the past. This prompted us to investigate the possible association of the polymorphism with falciparum malaria. We studied the di...

Type 2 diabetes (T2D) is a syndrome of multiple metabolic disorders and is genetically heterogeneous. India comprises one of the largest global populations with highest number of reported type 2 diabetes cases. However, limited information about T2D associated loci is available for Indian populations. It is, therefore, pertinent to evaluate the previously associated candidates as well as identi...

Drosophila ananassae is a cosmopolitan and domestic species distributed in the tropical, subtropical and mildly temperate regions. Population structure analysis in forty-five Indian natural populations of D. ananassae was performed employing three cosmopolitan inversions as markers. Pairwise FST analysis and genetic distance (D) values showed strong genetic differentiation. Though, lowermost va...

The number of valid species in the genus Echinometra (Echinodermata, Echinoidea) and their associated identification keys have been debated in the scientific literature for more than 180 years. As the phylogeny and dispersal patterns of these species have been widely used as a prominent model for marine speciation, new insights into their taxonomy have the potential to deepen our understanding ...

Most Indian groups descend from a mixture of two genetically divergent populations: Ancestral North Indians (ANI) related to Central Asians, Middle Easterners, Caucasians, and Europeans; and Ancestral South Indians (ASI) not closely related to groups outside the subcontinent. The date of mixture is unknown but has implications for understanding Indian history. We report genome-wide data from 73...

BACKGROUND: The tribal communities of South India are considered to be the original inhabitants of the Indian subcontinent, belonging to the most primitive Dravidian speaking communities. These Dravidian speaking forest dwelling tribal populations have remained isolated from any intermingling with other non-tribal communities. AIMS AND OBJECTIVES: We propose to understand the evolutionary proce...