IMPORTANCE: Every year, thousands of emergency department (ED) visits result in patients being discharged with oral antibiotic prescriptions. Published studies that assess the appropriateness these regimens are limited. PURPOSE: The purpose this study was to examine prescriptions written for from a community hospital’s ED. ENDPOINTS: primary objective determine overall percent appropriate Secon...

BACKGROUND Evidence for the impact of inappropriate antimicrobial therapy on bacteremia is mainly from studies in medical centers. We investigated the impact of inappropriate antimicrobial therapy on bacteremia in a community hospital. In particular, patients from the hospital's affiliated nursing home were sent to the hospital with adequate referral information. METHODS We performed a retros...

BACKGROUND Benzodiazepines are frequently prescribed to patients with drug use disorders. However, it has previously been difficult to distinguish whether this frequent prescribing was due to underlying psychiatric disorders or inappropriate prescribing. In a nationwide cohort study, we investigated the prescribing of benzodiazepines to patients with drug use disorders in connection with treatm...

BACKGROUND Proton-pump-inhibitors are often prescribed unnecessarily in hospitals, which in turn induces their prescriptions after discharge. OBJECTIVE To evaluate patients starting treatment with proton-pump-inhibitors during hospitalisation and proportion of inappropriate prescriptions. Patient risk factors and whether initiation in hospital induced their continuation in ambulatory care wer...

o bjectives: cases of antimicrobial resistance are increasing, partly due to inappropriate prescribing practices by dentists. the purpose of this study was to investigate the prescrib- ing practices and knowledge of dentists with regards to antibiotics. moreover, this study aimed to determine whether the prescriptions comply with the recommended guidelines and whether clinical audit can alter t...

BACKGROUND Age-related alterations in metabolism and excretion of medications increase the risk of adverse drug events in the elderly. Inappropriate polypharmacy and prescription practice entails increased burdens of impaired quality of life and drug related morbidity and mortality. The main objective of this trial is to evaluate effects of a tailored educational intervention towards general pr...

BACKGROUND As questions have been raised about the appropriateness of direct oral anticoagulant (DOAC) dosing among outpatients with atrial fibrillation, we examined this issue in patients being managed by primary care providers. METHODS AND RESULTS This was a retrospective cohort new-user study using electronic medical records from 744 Canadian primary care clinicians. Potentially inappropri...

OBJECTIVE To compare the appropriateness of antibiotic prescribing for upper respiratory tract infections (URTIs) in two countries with different prevalence of antimicrobial resistance: Denmark and Iceland. DESIGN A cross-sectional study. SETTINGS AND SUBJECTS General practitioners (GPs) in Denmark (n = 78) and Iceland (n = 21) registered all patients with URTI according to the Audit Projec...

OBJECTIVE 1/ To evaluate if empirical antibiotic prescription on admission to our intensive care unit (ICU) respects the local recommendations for antibiotic prescription and to identify predictors of nonadherence to these guidelines. 2/ To assess whether nonadherence to the guidelines is associated with increased in-hospital mortality due to the initial infection. MATERIALS AND METHODS This ...