objective: bipolar i disorder is a common disorder with a complex etiology. a genetic approach is gaining increasing importance in this disorder. the dysbindin gene, located at 6p22.3 is considered a susceptibility gene for schizophrenia. certain genotypes of dysbindin are thought to be associated with other psychoses such as bipolar disorders. this study intends to assess the association in pr...

objective(s): tyrosinase is a key enzyme in pigment synthesis. overproduction of melanin in parts of the skin results in hyperpigmentation diseases. this enzyme is also responsible for the enzymatic browning in fruits and vegetables. thus, its inhibitors are of great importance in the medical, cosmetic and agricultural fields. materials and methods: a series of twelve kojic acid derivatives wer...

Wilson disease is a metabolic disorder with an autosomal recessive genetic pattern and occurs in 1-4 of every 100000 individuals. Inactivation of the ATP7B gene leads to accumulation of the toxic copper to liver and brain causing hepatic and neurological complication. Therefore, most patients suffer from chronic hepatic inflammation and central nervous system disorder. Nowadays, up to ...

the ever increasing rate of power consumption has led to an increase in public exposure to extremely low frequency magnetic fields (elf-mfs) and brought severe concerns about their health effects. considering previous studies and the facts about potential health effects of these fields, the present study aimed to evaluate the elf-mf flux densities from power distribution lines near hospitals i...

the ever increasing rate of power consumption has led to an increase in public exposure to extremely low frequency magnetic fields (elf-mfs) and brought severe concerns about their health effects. considering previous studies and the facts about potential health effects of these fields, the present study aimed to evaluate the elf-mf flux densities from power distribution lines near hospitals in...

ôbjective: ït has been shown that serum and red blood cells’ level of ômega-3 fatty acids are low in people with schizophrenia. many studies have, therefore, attempted to explore the beneficial effects of these substances in the management of schizophrenia. however, the outcomes of the previous studies have not been clear cut. the present study is an attempt to retest this hypothesis by elimina...

in surrogate pregnancies genetic parents have little opportunity for early bonding with their infants either prenatally (in utero) or during the immediate postnatal period. procedures commonly used to induce lactation include both pharmacologic and nonpharmacologic methods often in combination. studies reporting induced lactation are sparse due to the rarity of augmented lactation. here we repo...