Noroviruses (NoVs), an important pathogenic agent of foodborne illness, lead to acute and chronic gastroenteritis in humans of all ages and to travelers’ diarrhea. Many genotypes exist in nature; GII.4 is widely known as the most predominant. Outbreaks mostly occur in semi-closed settings. Although the disease is self-limited to person, many cases have resulted in death, which has raised more c...

Two hundred cases of renal transplantation from living donors are reported from Shahid Hashemi Nejad Medical Center in Iran. There were 127 male and 73 female patients with 67% in the third and fourth decade of life. All patients received grafts from living donors with 114 cases of HLA haploidentical, 55 cases of HLA identical matches and 24 unrelated donors. One year patient and graft survival...

Epilepsy is a common neurologic disorder affecting approximately 1% of the population. The prevalence of active epilepsy in Kerman,Iran is 7.87/1000 individuals. The past decade has brought many advances to the treatment of epilepsy, including many new pharmacological agents. Lamotrigine is one of the new antiepileptic drugs. Lamotrigine has many side effects; the most important of which are al...

We count the number of alignments of N ≥ 1 sequences when match-up types are from a specified set S ⊆ N . Equivalently, we count the number of nonnegative integer matrices whose rows sum to a given fixed vector and each of whose columns lie in S. We provide a new asymptotic formula for the case S = {(s1, . . . , sN ) | 1 ≤ si ≤ 2}.

A simple procedure to tighten the Lagrangian bounds is proposed. The approach is interpreted in two ways. First, it can be seen as a reformulation of the original problem aimed to split the resulting Lagrangian problem into two subproblems. Second, it can be considered as a search for a tighter estimation of the penalty term arising in the Lagrangian problem. The new bounds are illustrated by a...