Type X collagen was prepared from medium of long-term cultures of embryonic chick tibiotarsal chondrocytes. Antibodies to type X collagen were raised and used in immunoperoxidase localization studies with embryonic and growing chick tibiotarsus. Strong anti-type X collagen reactivity was detected mainly in the region of hypertrophic chondrocytes, and to a lesser extent in the zone of calcified ...

The relation of the secretory immunoglobulin system in the colon to colorectal cancer and dysplasia has been examined by staining routine formalin-fixed, paraffin-embedded sections from cases of carcinoma, adenoma and ulcerative colitis for secretory component (SC), IgA and J chain. In carcinomas there was a close relation between SC synthesis and differentiation and a similar relation was appa...