introduction autoimmune haemolytic anemia (aiha) is a complex process characterized by an immune reaction against red blood cell self-antigens. the analysis of specimens, drawn from patients with cold auto-immune hemolytic anemia is a difficult problem for automated hematology analyzer. this paper was written to alert technologists and pathologists to the presence of cold agglutinins and its ef...

The phenomenon has dassically been produced in the rabbit by bacterial endotoxins (2) and results from the widespread occlusion of glomerular capillaries by dense fibrin deposits (3-5). Two basic conditions (3) appear essential for the development of the lesion: (a) the slow activation of intravascular coagulation with the formation of fibrin aggregates in the circulating blood, and (b) the inh...

Is the immune response altered in mental illness? Conversely, does an immune response affect mental function? Are any observed changes (both mental and immunological) the result of aetiological relationships? The answers to these questions are far from straightforward. The field is complex and evidence from immunological, psychiatric, psychological and neuroendocrinological studies is still sca...

Sera from cases of elephantiasis due to Wuchereria bancrofti infection promoted an intense adhesion of peripheral blood leukocytes to W. bancrofti microfilariae in vitro. A similar adhesion was also seen using sera from some normal persons living for several years in areas where filariasis is endemic. No such adhesion was evident with sera from microfilaria carriers or from normal subjects from...

The prominence of thrombosis in the pathogenesis of the Arthns phenomenon (1, 2), the alterations in the clotting mechanism seen in experimental anaphylaxis (3), and the occurrence of "fibrinoid" in lesions generally considered to be due to hypersensit ivity suggest tha t the interaction of antigen and antibody in vivo may in some manner init iate coagulation. Experiments to be reported here in...

BACKGROUND AND OBJECTIVE Current immunohematology practice dictates that serologic diagnosis of immune hemolytic transfusion reactions (IHTR) is based on the finding of a positive post-transfusion direct antiglobulin test (DAT). However, since DAT may fail to detect antibody-coated cells when they constitute a minor population amid a large number of non-sensitized ones, we investigated whether ...

Is the immune response altered in mental illness? Conversely, does an immune response affect mental function? Are any observed changes (both mental and immunological) the result of aetiological relationships? The answers to these questions are far from straightforward. The field is complex and evidence from immunological, psychiatric, psychological and neuroendocrinological studies is still sca...