The aim of the present study was to investigate blood parameters and subsequent fertility in cows with or without increased postpartum polymorphonuclear neutrophil activity. conducted 15 Brown Swiss between 1-3 lactations. Polymorphonuclear activities were assessed at 10±4 days before after parturition. which maintained their phagocytic oxidative burst activites compared prepartum period classi...

BACKGROUND Earlier, we had found high levels of circulating immune complexes (CICs) in the serum of type 2 diabetes mellitus patients along with a novel 43 kDa protein. METHODS Different tissues of alloxan-induced, diabetic, male albino rats (200-250 g in body weight) were collected for the present study. Tissue proteins were isolated and separated by 10% SDS-polyacrylamide gel electrophoresi...

asparaginase and amylase are widely used enzymes in various industries, which can be produced by endophytic fungi. in this study, the ability of producing these two enzymes in endophytic fungi isolated from six species of thymus has been reported for the first time in the world. among 89 isolates of the test, 34 isolates produced asparaginase among which m24 (fusarium subglutinans) displayed th...

the effect of salinity was assessed on the activity of some major antioxidant enzymes i.e., superoxide dismutase (sod), peroxidase (pod), catalase (cat), in the seedlings’ roots or shoots of three winter canola (brassica napus l.) cultivars, colvert (tolerant), symbol (semi tolerant) and agat (susceptible). seedlings were treated with 0 (control), 50, 100 and 150 mm nacl for 24 h in hydropoic c...

Resident macrophages isolated from uninfected animals produce large quantities of arachidonic acid (AA) metabolites. Immunizing animals with protein antigens or bacteria activates macrophages and causes an 80% reduction in the cyclooxygenase and lipoxygenase metabolites relative to resident cells. Since some products have been shown to modulate immune functions, we examined how the AA metabolic...

Partial purification of xylanase produced by Aspergillus niger strain AUMC 14230 is carried out with 80% saturation ammonium sulfate under pH5.0 as first step. The second step in partial Acetone 2.5/1 (v/v). last gill filtrations which give the highest specific from both enzymes.  Many factors affecting on purified enzymes. best activity was till 72 hrs and decreased (8.8% & 10.9%), respectivel...

CD73 (ecto-5'-nucleotidase) has recently been established as a promising immuno-oncology target. Given its role in activating purinergic signaling pathways to elicit immune suppression, antagonizing CD73 (i.e., releasing the brake) offers a complimentary pathway to inducing anti-tumor immune responses. Here, we describe the mechanistic activity of a new clinical therapeutic, MEDI9447, a human m...

Genetic studies on PARK genes have identified dysfunction in proteasomal, lysosomal, and mitochondrial enzymes as pathogenic for Parkinson's disease (PD). We review the role of these and similar enzymes in mediating innate immune signaling. In particular, we have identified that a number of PARK gene products as well as other enzymes have roles in innate immune signaling as well as DNA repair a...

water and soil salinity are two of the most important limiting factors in crop production. phosphatase enzymes are widely found in plants. phosphatase enzymes are responsible for de-phosphorylation of organic phosphate and altering it to mineral phosphate. germination experiments were conducted using two bread wheat cultivars, namely, iniya66 and ghods along with application of different nacl p...