Methods 36 patients with a history of immediate reactions to cefaclor were enrolled from Ajou University Hospital and Asan Medical Center, South Korea. Those with immediate hypersensitivity reactions to cefaclor were defined by a certain clinical history with or without specific IgE to cefaclor by immunoCAP system. Serum specific IgE, IgG1 and IgG4 levels to cefaclor-HSA conjugate were measured...

Allergy to milk is the only auto-allergic disease in cattle. It characterized by retention and absorption of itself, making proteins, especially alpha casein, have access bloodstream, resulting a type I hypersensitivity. The purpose this report describe case Here we four-year-old Jersey female bovine, which was pregnant weighing 400Kg. animal being treated at (hidden for revision) had history a...

The mouse sensitized by subcutaneous (sc) injection of lysozyme in emulsion of Freund's complete adjuvant (FCA) was shown by a modified footpad test to develop three kinds of hypersensitivities. Injecting lysozyme in 2.5-mul emulsion of Freund's incomplete adjuvant (FIA) into the footpad elicited strong footpad swelling in 30 min (anaphylactic reaction), in 3 hr (Arthus-type reaction) and in 24...

We studied the effects of prolonged topical application of tacrolimus on immediate hypersensitivity reactions. Tacrolimus, betamethasone or petrolatum was applied to the footpad of mice for up to 28 days after immunization, and the foot-swelling response to allergen was estimated. The reactions in tacrolimus-treated mice decreased significantly from day 14, while those in betamethasone-treated ...

Immediate hypersensitivity reaction to latex was first reported in Germany in 1927'. The next report appeared 1ll 1979 when Nutter2 described a case of contact urticaria due to the use of household gloves. Since then, there has been considerable increase in the number of reported cases of immediate type hypersensitivity to latex products. The clinical manifestations of the allergic reaction con...

Intralesional triamcinolone acetonide injection is indicated for multiple skin conditions such as keloid scars, alopecia areata, and hypertrophic lichen planus. Immediate hypersensitivity reaction remains uncommon. We report on a 24-year-old woman who had received multiple intralesional injections with triamcinolone acetonide (Kenacort) plus lidocaine for keloid scar treatment without any react...

Chemical respiratory allergy is an important occupational health problem, but there are currently available no validated methods for hazard identification. This is due in part to the fact that the relevant cellular and molecular mechanisms of sensitization of the respiratory tract have been unclear, with particular controversy regarding the role of IgE. There is now increasing evidence that res...

Objective Environmental and climatic changes have been occurring throughout the past 20 years in Japan. Correspondingly, the antigens that cause hypersensitivity pneumonitis might be changing. In an epidemiological survey of Japan in the 1980s, summer-type hypersensitivity pneumonitis (SHP) accounted for 74.4% of the cases of hypersensitivity pneumonitis. The epidemiological characteristics of ...

OBJECTIVES The purpose of this study was to characterize clopidogrel hypersensitivity and describe its successful management with oral steroids without clopidogrel discontinuation. BACKGROUND Hypersensitivity reactions to clopidogrel are poorly understood and present difficulty in management. METHODS Patients diagnosed with clopidogrel hypersensitivity after percutaneous coronary interventi...