A needle biopsy of a mass in the right breast of a 36-year-old woman revealed invasive ductal carcinoma (IDC), and approximately 20% of cancer cells showed unequivocal membranous staining with the HercepTest. After systemic therapy with trastuzumab and paclitaxel followed by FEC (fluorouracil + epirubicin + cyclophosphamide), a right mastectomy was performed. By histological and immunohistochem...

The family of innate lymphoid cells (ILCs) consists of a heterogeneous group of cytokine-producing cells that have features in common with adaptive T helper (Th) cells. Cytokines acting through the Janus kinase (JAK)/signal transducer and activator of transcription (STAT) pathways are key players in both Th and ILC biology. Observations in animal models, supported by evidence from humans, have ...

The morphological and proliferative effects of intratracheal cannulation (ITC) or intralaryngeal cannulation (ILC), with or without the instillation of saline or Fe2O3 particles in saline, were studied in Syrian golden hamsters. Instillation of Fe2O3 in saline at either airway level resulted in a similar distribution of Fe2O3 particles in all lung lobes. ILC produced laryngeal mucosal wounds. I...

PURPOSE We evaluated the utility of magnetic resonance imaging (MRI) and (18)F-fluorodeoxyglucose positron emission tomography/computed tomography ((18)F-FDG PET/CT) for the preoperative staging of invasive lobular carcinoma (ILC) of the breast and compared the results with those of invasive ductal carcinoma (IDC). METHODS The study included pathologically proven 32 ILCs and 73 IDCs. We compa...

This article reports the results of a small-scale quasi-experiment that tested the efficacy of the Prevention Options for Positives intervention. The experiment tested for the outcomes of group sessions combined with individual-level counseling (ILC) versus ILC-only for men who have sex with men who are HIV positive. Both arms of the intervention were based on behavior change theory and dealt s...

Invasive lobular carcinoma (ILC) is the second most common type of invasive breast cancer, having distinct prognostic and biologic implications. As an objective of the present work, we analyzed the clinicopathologic characteristics and prognostic factor of this invasive breast cancer variant. Clinical and morphological data of 25 cases of ILC collected during 2006-2011 were reviewed. Histopatho...

Indirect iterative learning control (ILC) facilitates the application of learning-type control strategies to the repetitive/batch/periodic processes with local feedback control already. Based on the two-dimensional generalized predictive control (2D-GPC) algorithm, a new design method is proposed in this paper for an indirect ILC system which consists of a model predictive control (MPC) in the ...

A two-dimensional (2-D) system theory based iterative learning control (ILC) method for a class of linear discrete-time uncertain systems is presented in this paper. We consider a general ILC scheme comprises a learning controller for betterment along iteration axis and two feedback controllers, a state feedback controller and a dynamic error compensator for robustness and convergence along tim...

The ILC Linac Group at SLAC is actively pursuing a broad range of R&D to improve the reliability and reduce the cost of the L-band (1.3 GHz) rf system. Current activities include the development of a Marx-style modulator and a 10 MW sheet-beam klystron, construction of an rf distribution system with adjustable power tap-offs and custom hybrids, tests of cavity coupler components to understand r...

Here, we illustrate the complexity of ILC subsets and discuss novel functions, focusing on emerging mechanisms of crosstalk with other immune cells and the microbiota. Furthermore, we highlight recent insights into the development of ILCs, including the common pathways they share as well as points of divergence between ILC groups and subsets.