BACKGROUND Allergy to zucchini (Cucurbita pepo), a member of the Cucurbitaceae family, has not previously been reported. We examined 4 patients complaining of allergic symptoms, such as oral allergy syndrome, nausea, diarrhea, or pruritus, after the intake of zucchini. OBJECTIVE After the confirmation of food allergy, we wanted to characterize zucchini allergens and examine possible cross-rea...

Asthma and chronic obstructive pulmonary disease (COPD) are highly prevalent chronic diseases in the general population. Both are characterized by similar mechanisms: airway inflammation, airway obstruction, and airway hyperresponsiveness. However, the distinction between the two obstructive diseases is not always clear. Multiple epidemiological studies demonstrate that in elderly people with o...

Abstract Background Pollen‐food allergy syndrome (PFAS) is caused by the cross‐reaction of specific IgE to pollen allergens with similar contained in fruits, vegetable, and nuts. The representative allergen responsible for this pathogenesis‐related protein (PR)‐10. Specific test using Gly m 4, soybean PR‐10, widely used diagnose soy allergy. We aimed investigate whether 4‐specific useful predic...

Hyper immunoglobulin-E (IgE) syndrome is an autosomal immune deficiency disease. It is characterized by an increase in IgE and eosinophil count with both T-cell and B-cell malfunction. Here, we report an 8-year-old boy whose disease started with an unusual skin manifestation. When 6 months old he developed generalized red, nontender nodules and pathologic report of the skin lesion was unremarka...

Background: The case we are reporting is about one of the rare manifestations severe combined immunodeficiency, Omenn syndrome (OS). Case presentation: A 43-days-old female presented with thick diffuse erythrodermic scaly ichthyosiform lesions on scalp, face, and trunk since birth. lymphadenopathy, splenomegaly, growth retardation as well eosinophilia increased serum IgE levels. pregnancy was p...