the prevalence of helicobacter pylori infection and the effect of its eradication on platelet count in 95 iranian patients with chronic refractory autoimmune thrombocytopenic purpura (critp) was investigated. 69 of 95 patients were infected with h.pylori (72.6%). h.pylori eradication was obtained in 69 infected critp pa tients who were not in remission and had platelet count below 100×109 at th...

BACKGROUND Administrative data may be useful for epidemiological studies of chronic idiopathic thrombocytopenic purpura (ITP). However, the quality of the recorded diagnoses needs evaluation. AIM We evaluated the validity in predicting chronic ITP of the International Classification of Diseases (ICD)-10 diagnoses of ITP in the Danish National Registry of Patients (NRP). METHODS We used the ...

Background. Immune thrombocytopenia (ITP), or idiopathic thrombocytopenic purpura, is a hematological autoimmune disease characterized by bleeding and an isolated decrease in platelet count <100 × 10 9 / l. The decision to start treatment for ITP depends on several factors. strategy based the clinical symptoms, with focus reducing risk of severe increasing counts. Aim. To evaluate efficacy 2...

A case is presented of a 13-year-old boy with chronic idiopathic thrombocytopenic purpura (ITP) who sustained traumatic labial luxation of both lower central incisors, with partial alveolar fracture resulting in displacement of the labial alveolar plate. Intravenous immunoglobulin (Fleibogamma, 1 g/kg body weight x 2 days) was administered, resulting in the patient's platelet count rising from ...

The purpose of this study was to estimate the incidence and to establish which factors were associated with an increased risk of hemorrhagic complications in an historic cohort of 117 consecutive and unselected patients with chronic idiopathic thrombocytopenic purpura (ITP). Sixty-eight patients (58%) underwent medical treatment and/or splenectomy and 33 (48% of treated) achieved a complete sta...

Subdural hematoma (SDH) is a rare complication of immune thrombocytopenic purpura (ITP) the incidence being around 2%. Although SDH usually occurs secondary to trauma, in bleeding disorders it may occur spontaneously. Here we report subdural hematoma in two uncommon settings, one patient with systemic sclerosis developing secondary ITP and consequently subdural hematoma and the other patient wi...

Prof. Dr. Şinasi Özsoylu, Hacettepe Children’s Hospital, TR-06100 Ankara (Turkey) I have read with interest Barrios et al.’s paper on the ‘Treatment of Acute Idiopathic Thrombocytopenic Purpura with High-Dose Methylprednisolone and Immuno-globulin’ in a recent issue of the journal [1993;89:6-9]. The authors concluded that ‘the combined therapy resulted in rapid increments in the platelet counts...

BACKGROUND Several studies showed some chronic idiopathic thrombocytopenic purpura (ITP) patients with complete platelet recovery after Helicobacter pylori (H. pylori) eradication and cited the cause of persistent thrombocytopenia as inability to eradicate H. pylori. So we studied H. pylori infection status in pediatric ITP patients at diagnosis and address whether such infection played a role ...

We report a case of idiopathic thrombocytopenic purpura (ITP) accompanied by steroid-induced avascular necrosis of the femoral head in a 68-year-old woman. Extremely low platelet counts of ITP patients prohibit any surgical interventions. Her platelet count was 25,000/μL. We performed a total hip arthroplasty with high-dose immunoglobulin therapy and transfusion of platelet concentrates. Her pl...