Introduction Uveitis is the most common extraarticular manifestation of juvenile idiopathic arthritis (JIA). The nature of JIAassociated uveitis is often insidious and asymptomatic, and baseline predictors can aid early diagnosis of eye disease for prompt and adequate treatment. Antihistone antibodies (AHA) are among subtypes of antinuclear antibodies (ANA) identified in children with JIA. An a...

Background Uveitis is a common extra-articular feature in juvenile idiopathic arthritis (JIA), particularly in female patients with the extended oligoarticular subtype. A significant number of patients already have ocular complications at time of diagnosis of uveitis. JIA-associated uveitis carries significant ocular morbidity that can progress into adulthood. Treatment with immunosuppressive a...

Introduction Juvenile idiopathic arthritis (JIA) is a chronic autoimmune disease of children and adolescents with primary joints involvement and various manifestations. Uveitis is of extra-articular signs characterized by eye inflammation. Standard antirheumatic drugs in combination with local therapy are effective in 60%. When these drugs are ineffective, genetically engineered drugs are used ...

BACKGROUND Although TINU syndrome is characterized by idiopathic TIN with bilateral anterior uveitis, few reports have provided a comprehensive summary of the features of this disorder. Previous reports have suggested that many Japanese patients had HLA-A2 and -A24 (7), but there is no evidence. CASE REPORT A 44-year-old female was referred to our hospital due to renal dysfunction in March 20...

AIMS To determine the burden of disease in a unique sample of patients with uveitis from a rural South African setting. METHODS Data in this cross-sectional study were collected from patients presenting with uveitis (n=103) at the ophthalmology outpatient department of three hospitals in rural South Africa. Demographic and clinical data were collected, and laboratory analysis of aqueous humou...

AIM To assess the efficacy of low dose methotrexate (MTX) therapy for children with chronic anterior and intermediate uveitis. METHODS A retrospective case review of 10 children who received MTX for chronic uveitis at a tertiary referral centre was performed. The following data were recorded for each patient: age, sex, race, duration of uveitis, primary diagnosis, anatomical localisation of u...

PURPOSE To study uveitis prevalence in the local population with spondyloarthritis and its temporal relationship with joint complaints. METHODS We reviewed seventy-seven charts of spondyloarthropathy patients from the rheumatology clinic of the "Hospital Universitário Evangélico de Curitiba" for spondyloarthritis class, patients' sex and age, occurrence of uveitis and its location and relatio...

Abstract Background Non-infectious uveitis is a well-reported cause of blindness in more developed countries, however data from sub-Saharan Africa lacking. Here we aim to describe the diseases associated with paediatric non-infectious and effect currently available treatment this setting. Methods A retrospective observational analysis children January 2010 December 2017, attending tertiary rheu...