BACKGROUND According to current guidelines, new second-generation oral Hi-antihistamines, as well as intranasal corticosteroids (ICSs), are recommended for the treatment of allergic rhinitis (AR) in adults and children. OBJECTIVE To assess changes in AR severity, in addition to nasal symptoms and health-related quality of life (HRQoL), after 4 weeks of treatment with rupatadine in a cohort of...

Although sublingual immunotherapy (SLIT) is accepted to be a viable alternative of specific-allergen immunotherapy, the efficacy of long-term SLIT in asthmatic children is not well established. The efficacy of 3 yr of SLIT in addition to pharmacotherapy was compared with pharmacotherapy alone in a prospective, open, parallel-group, controlled study. Children with asthma aged 4-16 yr, sensitive ...

Ciclesonide is a nonhalogenated synthetic inhaled corticosteroid (ICS) that has been approved by the US Food and Drug Administration for the treatment of all severities of persistent asthma. It is available as a hydrofluroalkane pressurized metered-dose inhaler in two strengths, 80 mcg/activation and 160 mcg/activation, with the recommenced dosage being two inhalations twice-daily. It is a prod...

The electronic state spectroscopy of carbonyl sulphide, COS, has been investigated using high resolution vacuum ultraviolet photoabsorption spectroscopy and electron energy loss spectroscopy in the energy range of 4.0-10.8 eV. The spectrum reveals several new features not previously reported in the literature. Vibronic structure has been observed, notably in the low energy absorption dipole for...

Recent years have seen a number of cyber attacks targeting Industrial Control Systems (ICSs). Reports detailing the findings from such attacks vary in detail. Handson experimental research is, therefore, required to better understand and explore security challenges in ICSs. However, real-world production systems are often offlimits due to the potential impact such research could have on operati...

Industrial Control Systems (ICSs) are computers managing many critical infrastructures like power plants, aeroplanes, production lines, etc. While ICS were specialised hardware circuits without internet connection in former times, they are nowadays commodity computers with network connection, TCP/IP stack, and a full operating system, making them vulnerable to common attacks. The defensive mech...

BACKGROUND The prevalence of thyroid cancer has increased very rapidly in Korea. However, there is no published report focusing on thyroid cancer mortality in Korea. In this study, we aimed to evaluate standardized thyroid cancer mortality using data from Statistics Korea (the Statistical Office of Korea). METHODS Population and mortality data from 1985 to 2010 were obtained from Statistics K...

Recently, Industrial Control Systems (ICSs) have been changing from a closed environment to an open because of the expansion digital transformation, smart factories, and Internet Things (IIoT). Since security accidents that occur in ICSs can cause national confusion human casualties, research on detecting abnormalities by using normal operation data learning is being actively conducted. The sin...

The high prevalence of COPD together with its high level of misdiagnosis and late diagnosis dictate the necessity for the development and implementation of clinical practice guidelines (CPGs) in order to improve the management of this disease. High-quality, evidence-based international CPGs need to be adapted to the particular situation of each country or region. A new version of the Russian Re...

Inhaled corticosteroids (ICSs) are associated with rare systemic adverse drug effects (ADEs) but, more commonly, are associated with oropharyngeal ADEs. The objective of this study was to determine the treatment patterns employed by physicians for ICS-induced oropharyngeal ADEs in order to ultimately determine their economic burden. A panel of 15 physicians completed three rounds of a Delphi pr...