In this paper, we considered the half logistic model and derived a probability density function that generalized it. The cumulative distribution function, the $n^{th}$ moment, the median, the mode and the 100$k$-percentage points of the generalized distribution were established. Estimation of the parameters of the distribution through maximum likelihood method was accomplished with the aid of c...

Thalidomide is the treatment of choice for severe or recurrent erythema nodosum leprosum. Its use has been associated with deep vein thrombosis in patients with blood disorders, however, particularly when used in combination with corticosteroids or chemotherapy. We describe a case of deep vein thrombosis in a 43-year-old man with lepromatous leprosy who was being treated with thalidomide and pr...

objective: serum leptin concentration reflects the body fat mass. there is controversial reports about the insulin effect on serum leptin concentration. we wanted to examine the effect of insulin therapy on serum leptin in children with new onset type i diabetes. materials and methods: this was a cross-sectional study in children's medical center on 34 children who had new onset type i dia...

Murine leprosy is analogous to hum an lepromatous leprosy by similarities in host cell reaotions and some characteristics of causative agents. As in the lcsions of lepromatous lcprosy so also in the lesions of murine leprosy there arc innumerable undigested bacilli and large amounts of lipids in maerophages. The present studies were initiated as a part of a series of analysis of the chemical co...

In a number of papers since 1952 Sagher and associa tes (18. 27. 29-35 ) have called attention to a specific tissue response of the noninvolved skin of lepromatous leprosy on intradermal injection with various agents. Tuberculin , leishmanin , milk, p eptone and living leishmanial leptomonads elicited a prelepromatous or lepromatous infiltration, usually without bacilli, at the site of the inje...

A 49-year-old man with lepromatous leprosy treated with dapsone monotherapy for 12 years (1967 to 1979) reported in the hospital in 2003, with relapsed disease. A slit skin smear showed a bacteriological index of 4+. Biopsies from skin lesions before and after anti-leprosy therapy showed features of lepromatous leprosy. Both biopsies showed unusual features of bacillary clumps in epidermal cell...