نتایج جستجو برای: hypervitaminosis a

تعداد نتایج: 13431831  

2013
Anthony R. Mawson

Mefloquine use has been linked to severe gastrointestinal and neuropsychiatric adverse effects, including cognitive disturbances, anxiety, depression, psychosis, and violence. The adverse effects of the drug are thought to result from the secondary consequences of hepatocellular injury; in fact, mefloquine is known to cause a transient, anicteric chemical hepatitis. However, the mechanism of me...

2014
Bryan Gannon Chisela Kaliwile Sara A Arscott Samantha Schmaelzle Justin Chileshe Ngándwe Kalungwana Mofu Mosonda Kevin Pixley Cassim Masi Sherry A Tanumihardjo

BACKGROUND Biofortification is a strategy to relieve vitamin A (VA) deficiency. Biofortified maize contains enhanced provitamin A concentrations and has been bioefficacious in animal and small human studies. OBJECTIVE The study sought to determine changes in total body reserves (TBRs) of vitamin A with consumption of biofortified maize. DESIGN A randomized, placebo-controlled biofortified m...

Journal: :Investigative ophthalmology 1963
J W ECONOMON A M SILVERSTEIN L E ZIMMERMAN

A high incidence of band keratopathy was observed in a rabbit colony being utilized in uveitis experiments. Unrelated to the uveitis, the animals had developed, in addition to the corneal lesions, deposits of calcium in the kidneys, arterial tree, trachea, and smooth muscle of the intestine suggestive of hypercalcemia due to an accidental hypervitaminosis D. The clinical and histopathologic cha...

Journal: :Journal of embryology and experimental morphology 1965
D M Kochhar E M Johnson

IN the laboratory many teratogenic procedures have been found to produce cleft palate in conjunction with other congenital malformations (Kalter & Warkany, 1959), but only in embryos of cortisone treated mice has this malformation been reported to occur singly (Baxter & Fraser, 1950). However, a carefully controlled treatment with hypervitaminosis A can produce a high incidence of cleft palate ...

Journal: :Anticancer research 2004
G Bartolini K Ammar B Mantovani F Scanabissi A M Ferreri P Rocchi M Orlandi

Vitamin A and its metabolic forms, like all-trans retinoic acid (ATRA), are used with promising results in the treatment of many tumors. Two major problems in the clinical use of retinoids are that the doses needed for successful treatment are often toxic, leading to "hypervitaminosis A syndrome" and that patients often develop drug resistance. In order to find compounds that can overcome these...

Journal: :The Journal of Clinical Endocrinology & Metabolism 2012

نمودار تعداد نتایج جستجو در هر سال

با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید