To determine the mode of inheritance of hypertrophic cardiomyopathy 193 first degree relatives (parents, siblings, and offspring) of 50 patients with hypertrophic cardiomyopathy were assessed by clinical examination, electrocardiography, M mode and cross sectional echocardiography, and necropsy when available. Thirty nine (20%) first degree relatives had hypertrophic cardiomyopathy--37% of pare...

Hypertrophic cardiomyopathy corresponds to myocardial hypertrophy >15mm or >13mm in case of familial hypertrophic (HCM).We report the a 31-year-old patient with no cardiovascular risk factors and notable history who was admitted emergency room for management prolonged resting chest pain associated electrical changes electrocardiogram (EKG)given clinical symptomatology overshift mirror ima...

JOURNAL OF WOUND CARE JANUARY, VOL 9, NO 1, 2000 Most wound healing is well controlled, but over-abundant deposition of collagen may result in hypertrophic or keloid scarring.1 These scars are raised, hard, lumpy and erythematous, and pruritis is invariably a distressing symptom.2 The prime clinical feature distinguishing keloid from hypertrophic scarring is that keloid scar tissue progressivel...

Introduction Reconstruction of large bone defects using tissue engineered or native bone tissue remains a major challenge. An alternative approach is to create a hypertrophic cartilage template which can undergo mineralisation. Formation of hypertrophic cartilage occurs during natural or induced repair of bone. This tissue can survive a low oxygen environment and produces factors which stimulat...

. Arad M, Maron BJ, Gorham JM, et al. Glycogen storage diseases presenting as hypertrophic cardiomyopathy. N Engl J Med 2005;352:362–72. . Dougu N, Joho S, Shan L, et al. Novel LAMP-2 mutation in a family with Danon disease presenting with hypertrophic cardiomyopathy. Circ J 2009;73:376–80. . Maron BJ, Seidman JG, Seidman CE. Proposal for contemporary screening strategies in families with hyper...

We report the case of a 49-year-old male with clinical and histological findings consistent with hypertrophic lupus erythematosus (HLE). HLE must be clinically and histologically differentiated from keratoacanthoma, hypertrophic lichen planus, squamous cell carcinoma and plaque type psoriasis. CD123 positivity and transepidermal elimination of elastin have recently been reported as tools to dis...

The expression of nerve growth factor receptor in colon from 20 patients with Hirshsprung's disease and 10 controls was studied immunohistochemically. The myenteric and submucous plexuses in the ganglionic bowel and hypertrophic nerve trunks in the aganglionic bowel displayed strong expression of nerve growth factor receptor. The most important finding was the identical localisation of nerve gr...

Herpes simplex virus type 2 (HSV-2) infections are frequent in HIV (human immunodeficiency virus) infected patients. In those cases, genital herpes may have an atypical clinical presentation. Hypertrophic and vegetating variants are unusual. The authors describe a case of hypertrophic perianal herpes in an HIV patient with unsatisfactory response to acyclovir and valacyclovir, successfully trea...

Introduction. Although fractures of humeral shaft show excellent results with conservative management, nonunion does occur. Case Report. We bring forth the case of a young male with a 1.5-year-old hypertrophic nonunion of the humerus mimicking an enchondroma. The initial X-ray images of the patient appeared to be an enchondroma, which only on further evaluation and histopathological analysis wa...

Epithelioid hemangioendothelioma is a rare vascular tumor, which occurs in the lung, liver, bone, and soft tissue. Hypertrophic osteoarthropathy is a syndrome characterized by subperiosteal new bone formation, joint effusion and clubbing, and may be associated with cyanotic heart disease, chronic pulmonary disease, liver disease, and other miscellaneous diseases. The activation of endothelium a...