Erythrocyte contents and ouabain-insensitive transport pathways were measured in 120 white and black normotensives and hypertensives. Mean maximal sodium-stimulated lithium-sodium countertransport rate was higher in white hypertensives than in white normotensives, and countertransport was significantly positively correlated with mean arterial pressure in whites. Values similar to those in white...

Arterial stiffness increases with ageing and hypertension. Regular physical activity has been recommended as an important management component of hypertension. The purpose of this study was to examine the acute impact of maximal dynamic exercise and the effect of 20 weeks of aerobic exercise on arterial stiffness of the carotid and brachial arteries in older hypertensives. Nine previously seden...

S egmental variation in left ventricular (LV) wall thickness is important in characterizing hypertrophic cardiomyopathy, post-infarction remodeling, and myocardial noncompaction. In each of these disorders, cardiac magnetic resonance (CMR) has greatly extended our understanding due to its ability to comprehensively assess LV structure, function, and myocardial composition over the entire LV cha...

This study reports the determination of plasma 18-hydroxycortisol (18-OHF) using a new and easy enzyme-linked immunosorbent assay (ELISA) method in primary aldosteronism and compares the values found in essential hypertensives and normotensive controls. In primary aldosteronism, we evaluated usefulness of plasma 18-OHF determination and the dexamethasone suppression test in the diagnosis of glu...

Eight normotensive and eight essential hypertensive humans were studied when on high and low sodium intake. Total 24-hr exchangeable body sodium, blood volume, serum sodium concentration, hematocrit, body weight, and mean arterial pressures, when the subjects were supine and upright, were measured. Plasma and nonplasma sodium fractions, nonplasma weight, and plasma, cell, and whole blood volume...

Levels of hypertension treatment and control have been noted to vary between Europe and North America, although direct comparisons with similar methods have not been undertaken. In this study, we sought to estimate the relative impact of hypertension treatment strategies in Germany, Sweden, England, Spain, Italy, Canada, and the United States by using sample surveys conducted in the 1990s. Hype...

The circulatory effects of blocking cardiac and peripheral autonomic effectors were studied in 32 subjects with established essential hypertension, and in 15 normotensives. The mean resting arterial pressure, heart rate and total peripheral resistance index (TPRI) were significantly higher in the hypertensives, but cardiac index was the same in both groups. In subjects with blocked cardiac effe...