We present a systematic review of observational studies of hypericum extracts in the treatment of depressive disorders. We included non-randomized studies with at least 100 patients suffering from depressive disorders treated with hypericum mono-preparations for at least 4 weeks, which reported clinical outcomes. Potentially relevant studies were identified through searches in electronic databa...

Muğla İli Ula İlçesi Merkez ve bağlı mahallelerinde 2016-2018 yılları arasında yaptığımız etnobotanik alan çalışmamızda farklı yaş sosyal kategorilerden kişilerle görüşülmüştür. Çalışma alanımız olan Ula’da 53 familyaya ait 123 bitki türü kaydedilmiştir. Bu bitkilerden 70 tanesi yörede doğal yayılışa sahip olup,45 de halk tarafından yetiştirilmektedir.10 ise hiçbir şekilde yetiştirilmemektedir....

The involvement of brain-derived neurotrophic factor (BDNF) in different central nervous system (CNS) diseases suggests that this neurotrophin may represent an interesting and reliable therapeutic target. Accordingly, the search for new compounds, also from natural sources, able to modulate BDNF has been increasingly explored. The present review considers the literature on the effects of botani...

Two bioactive xanthones from Hypericum perforatum have been synthesized by direct routes. Benzo[c]xanthone 5 can be prepared from intermediate 4.