Leydig cell tumors of the ovary account for less than 0.1% of all ovarian tumors (1). We present two cases in which patients had markedly elevated serum testosterone levels and frank hirsutism. Both cases revealed right ovarian Leydig cell tumors upon oophorectomy with post-surgical resolution of hypertestosteronemia. While rare and difficult to diagnose, androgen secreting tumors should be sus...

OBJECTIVE Women with polycystic ovary syndrome (PCOS) seeking health care in the United States may be more obese and hyperandrogenic than those present in the general population. We aimed to assess the impact of referral bias on European women with functional androgen excess disorders. DESIGN Cross-sectional study. METHODS We studied two groups of patients: i) 368 consecutive patients refer...

This report describes the case of a 28 year old woman with virilisation occurring in two successive pregnancies. Recurrent maternal virilisation is rare (seven previous reports) and this case is unique in its severity. Differential diagnoses include ovarian disease and fetal aromatase deficiency. New techniques to exclude a fetal cause were used in this case. This patient presented during the t...

Polycystic Ovary Syndrome (PCOS) is a reproductive, hormonal, and metabolic disorder frequently associated with insulin resistance, hyperandrogenism, chronic inflammation, oxidative stress. Resveratrol naturally occurring polyphenolic stilbene found in trace amounts some food items. It has been extensively used as treatment option for disorders but its use PCOS limited. This review emphasizes t...