نتایج جستجو برای: hyper ige
تعداد نتایج: 38192 فیلتر نتایج به سال:
in this paper rst we de ne the notions of positive implicativehyper mv -ideals of types 1,2,3 and 4 in hyper mv -algebras and we investigatethe relationship between of them . then by some examples we show that thesenotions are not equivalent. finally we give some relations between these notionsand the notions of (weak) hyper mv -ideals and (weak) hyper mv -deductivesystems of hyper mv -algebras.
Abstract There are two forms of hyper-immunoglobulin E syndromes (HIES): a dominant form (AD-HIES) is caused by mutations in signal transducer and activator transcription 3 (STAT3), recessive (AR-HIES) dedicator cytokinesis 8 (DOCK8). DOCK8 autosomal hyper IgE syndrome patients have more symptomatic neurologic disease than those with STAT3 deficiency. Involvement the central nervous system HIES...
Abstract Dysregulated expansion and/or activation of mast cells have detrimental consequences in allergic disease. In humans, homozygous or compound heterozygous deletions DOCK8 cause a combined immunodeficiency characterized by disorders. Based on this evidence, we hypothesized that may be negative regulator cell function. To address hypothesis, used mice with loss-of-function mutation Dock8 (...
BACKGROUND Olmsted syndrome is a rare congenital skin disorder presenting with periorifical hyperkeratotic lesions and mutilating palmoplantar keratoderma, which is often associated with infections of the keratotic area. A recent study identified de novo mutations causing constitutive activation of TRPV3 as a cause of the keratotic manifestations of Olmsted syndrome. METHODS Genetic, clinical...
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