background: melatonin has receptors in substantia nigra pars compacta (snc) and regulates development of dopaminergic (da) neurons. this study was undertaken to determine ability of melatonin to protect snc dopaminergic neuron loss induced by estrogen deficiency in ovariectomized rats. methods: female rats were randomized into four groups of seven each: control, ethanol sham, ovariectomy (ovx) ...

the aim of this study was to analyze the stress response during 3 hours net confinement stress and recovery period of 22 hours in normal (std) and in 17α-hydroxylase deficient common carp (e5). fish were raised for 6 months and sampled at t0 (control, unstressed), 5 minutes, 20 minutes, 1 hour and 3 hours of exposure to net confinement, and after 1 hour, 4 hours, and 22 hours of recovery. at ev...

Congenital adrenal hyperplasia is one of the most frequently inherited diseases. It is characterized by a severe decline in cortisol secretion, which results in a compensatory increase in ACTH and consequent adrenal growth (hyperplasia). Here we describe the first case of 11beta-hydroxylase deficiency that is caused by an unequal cross-over of the genes encoding aldosterone synthase (CYP11B2) a...