After spontaneous vaginal delivery, a 32-week-gestation female baby presented immediately with respiratory distress, APGAR scores 0 (1 min) and 2 (5 min), generalized skin oedema and bilateral pleural effusion. The prenatal history was unremarkable. The clinical diagnosis was nonimmune hydrops fetalis, and treatment with mechanical ventilation, surfactant, prostaglandin and supportive measures ...

Parvovirus B19 is a small DNA virus. Infection with parvovirus B19 during pregnancy may cause serious complications in the fetus, including hydrops fetalis and fetal death. The purpose of the present study is to clarify the clinical manifestations and outcomes of parvovirus B19 infection during pregnancy. This prospective study enrolled 478 women with suspected B19 infections during pregnancy b...

BACKGROUND The wide variation and nonspecific nature of many of the associated ultrasonographic findings complicate prenatal diagnosis of Noonan syndrome. The aim of the present study was to define the rate of prenatal diagnosis of heart malformations in cases diagnosed postnatally with Noonan syndrome. METHODS English-language literature review of 29 cases of Noonan syndrome examined prenata...

Increased nuchal translucency (NT) is present in about 50% of cases with trisomy 21. Very often the nuchal edema evolves in hydrops fetalis until the second trimester. Furthermore, a small amount of cases with a normal NT and trisomy 21 exhibit anatomical anomalies. We present a case of a 21-year-old woman, nulliparous, with a history of one termination of pregnancy and a smoking quitter. The p...

QUESTION One of my pregnant patients came for a routine prenatal visit at 20 weeks' gestation. Near the end of the consultation, she asked me about "slapped cheek" disease and pregnancy, as her son had been diagnosed with fifth disease the previous week. What is the current guideline for pregnant women exposed to parvovirus B19? ANSWER The rate of vertical transmission during maternal parvovi...

OBJECTIVE The purpose of this study is to evaluate the effect of prenatal steroid treatment in fetuses with sonographically diagnosed congenital cystic adenomatoid malformations (CCAMs). METHODS This was an institutional review board-approved retrospective review of 372 patients referred to the University of California, San Francisco (UCSF), for fetal CCAM. Inclusion criteria were (1) a predo...

Since the initial study by Nakashima et al. [1] who demonstrated that endolymphatic hydrops in patients with Ménière’s disease can be visualized using MR imaging following an intratympanic injection of gadolinium, this topic has gained strong clinical interest internationally [2–13]. The two most common sequences used in the evaluation of endolymphatic hydrops are a 3D Fluid Attenuated Inversio...

To improve the imaging protocol for the evaluation of endolymphatic hydrops after intravenous administration of a gadolinium-based contrast agent, we modified our previously reported hybrid of reversed image of positive endolymph signal and native image of positive perilymph signal (HYDROPS) method. Although the scan time of the new protocol was half that of the previous one, there were no sign...