One of the main challenges in chemotherapy is the delivery of effective doses of cytotoxic agents to the tumor site and simultaneously to minimize the side effects on normal cells. The use of drug delivery systems (DDS) can improve the pharmacological properties of many agents, modifying their pharmacokinetics and biodistribution. Among the DDS available, liposomes are one of the most used and ...

purpose: to compare the optical properties of hydrophilic and hydrophobic intraocular lenses (iols) containing uv-absorber and to determine their chemical composition. methods: optical properties of different foldable hydrophilic and hydrophobic as well as non-foldable hydrophobic polymethylmetacrylate (pmma) iols were evaluated in three powers of 15, 22 and 25 diopters. optical properties were...

polyacrylonitrile (pan) membranes with nano-porous surface and high hydrophilicity were fabricated by addition of polyoxyethylene (40) nonylphenyl ether (igepal) as an additive in the casting solution. the membranes were prepared from pan/igepal/1-methyl-2-pyrrolidone (nmp) via phase inversion induced by immersion precipitation technique. pure water was used as coagulation medium. the effects o...

BACKGROUND Following the terror attack on Utøya on 22 July 2011, the Norwegian Directorate of Health recommended a proactive model of follow-up in the municipalities. According to this model, crisis teams were to rapidly contact the survivors, and all survivors were to be assigned a fixed contact person in the municipality. The aim was to ensure early assistance and continuity of follow-up. In ...

Hydrogels have found promising applications in drug delivery due to their biocompatibility, high drug loading capability, and tunable release profiles. However, hydrogel-based carriers are primarily employed for delivering hydrophilic payloads while hydrophobic drugs cannot be efficiently delivered due to the lack of hydrophobic domains within conventional hydrogel matrices. Herein, we report t...

Article history: Received on: 12/06/2013 Revised on: 16/09/2013 Accepted on: 17/10/2013 Available online: 31/10/2013 Tuberculosis has metamorphosized over the decades from drug resistant to multidrug resistant to the lethal extensively drug resistant forms lately. With scarce newer anti-TB drugs emerging, there is a pressing need to ameliorate the current treatment therapy by modulating the for...