Solutions of 0.012% hydrazine sulfate, 0.001% 1,2-dirnethylhydrazine dihydrochloride, and 0.5% isonicotinic acid were given continuously in the drinking water of 9-, 7-, and 5-week-old randomly bred Syrian golden hamsters for the remainder of their lifetime. The consumption of hydrazine sulfate and isonicotinic acid was without any significant carcinogenic action, while 1,2-dimethylhydrazine di...

The goal of the EU Horizon2020 project Rheform is the replacement of hydrazine with liquid propellants based on ammonium dinitramide (ADN) for orbital and launcher propulsion systems. Hydrazine and its derivatives are the standard propellants for spacecraft propulsion system since the 1960s, but they are highly toxic and carcinogenic. New regulations will lead to restriction of their use in the...

3-Methyl-1-phenylpyrazol-5-one and its derivatives prepared using ethyl acetoacetate, phenyl hydrazine and its derivatives. Ethyl acetoacetate reacted with phenylhydrazine at reflux temperature to give 3-methyl-1-phenylpyrazol-5-one crude and recrystlized from diluted ethanol to give pure 3-methyl1-phenylpyrazol-5-one. Different pyrazolone derivatives were prepared by using different phenyl hyd...

Azines (2,3-diazabuta-1,3-dienes) are a widely used class of compounds with conjugated C=N double bonds. Herein, we present a direct synthesis of azines from alcohols and hydrazine hydrate. The reaction, catalyzed by a ruthenium pincer complex, evolves dihydrogen and can be run in a base-free version. The dehydrogenative coupling of benzylic and aliphatic alcohols led to good conversions and yi...

Hydrazine and its derivatives, as harmful substances, seriously risk the health of humans environment. On basis admirable luminescent properties low biological harmfulness biphenyl moiety, a moiety can be combined with naphthalene ring via chalcone scaffold easily traced by nucleophilic group. Therefore, chalcones (BPCs) decorated various systems fluorescent sensors for hydrazine are synthesise...

In a recent article in the Journal of Biological Chemistry 2 is reported a study of the influence of hydrazine upon the intermediary metabolism in the dog, by Professor F. P. Underhill and I. S. Kleiner, in which it is shown that although this poison produces extensive anatomical alterations in the liver of dogs, yet it causes little change in the partition of urinary nitrogen and sulphur, beyo...

Hydrazine functionalized Schiff base, 1,2-di(benzylidene)hydrazine has been synthesized through a condensation between hydrazine and benzaldehyde under reflux, structurally characterized. The crystal structure analysis reveals that the base crystallizes in an orthorhombic system with Pbcn space group. Crystal data for C14H12N2: = 13.130(2) Å, b 11.801(2) c 7.5649(16) V 1172.1(4) Å3, Z 4, T 298....