Gestational trophoblastic disease (GTD) represents a spectrum of lesions characterised by an abnormal proliferation of trophoblast, including complete hydatidiform mole, partial hydatidiform mole, invasive hydatidiform mole, choriocarcinoma, placental site trophoblastic tumour, epithelioid trophoblastic tumour, placental site nodule and plaque, and exaggerated placental site reaction. Complete ...

BACKGROUND Distinction of hydatidiform moles (HMs) from non-molar abortions and sub-classification of HMs are important for clinical practice; yet, diagnosis based solely on morphology is affected by interobserver variability. The objective of this study was to determine the role of DNA flow cytometry in distinguishing molar from non-molar pregnancies. MATERIALS AND METHODS This retrospective...

initial management, incidence and review of hydatidiform mole, chorioadenoma and destruens and chorio carcinoma in mirza kochek khan hospital department of ob.gyn and gynecology oncology of women's hospital tehran-iran school of medicin from september 1985 to march 1990, 209 patients received primary management for hydatidiform mole at oncology department of mirza kochek khan hospital medi...

Presentation of hydatidiform mole as tubal ectopic pregnancy is very rare. These patients usually present with ectopic pregnancy and are later diagnosed with hydatidiform mole on the basis of histological examination following surgery. We present the case of a 32-year-old female who presented with abdominal pain and vaginal bleed since 2 days of presentation. She was vitally stable. There was m...

Background Distinction of hydatidiform moles (HMs) from non-molar abortions and sub-classification of HMs are important for clinical practice; yet, diagnosis based solely on morphology is affected by interobserver variability. The objective of this study was to determine the role of DNA flow cytometry in distinguishing molar from non-molar pregnancies. MaterialsAndMethods This retrospective stu...

Choriocarcinoma is a unique neoplasm that can occur after a pregnancy, as a component of germ cell tumors, or follow the trophoblastic differentiation of neoplastic somatic cells that completely lose their normal phenotype and produce hCG. Gestational Choriocarcinoma (GC) and Nongestational Choriocarcinoma (NGC) are pathologically and morphologically similar, but differ in genetic origin, immun...

BACKGROUND The incidence of hydatidiform mole (HM) differs among regions but has declined significantly over time. In Thailand, the initiation of universal health coverage in 2002 has resulted in a change of medical services countrywide. However, impacts of these policies on gestational trophoblastic disease (GTD) cases in Thailand have not been reported. This study aimed to find the incidence ...