نتایج جستجو برای: hybridoma

تعداد نتایج: 2172  

Journal: :Proceedings of the National Academy of Sciences of the United States of America 1981
E Razin C Cordon-Cardo R A Good

A pure population of mast cells was obtained after 14 days of culturing mouse bone marrow cells in the presence of medium derived from concanavalin A-stimulated mouse spleen cells. The cells were characterized as mast cells by their morphologic appearance and histologic staining, by their histamine content (450 ng per 10(6) cells) and by the demonstration of IgE receptors on their surface (150,...

2014
Georges Hattab Annabelle Y. T. Suisse Oana Ilioaia Marina Casiraghi Manuela Dezi Xavier L. Warnet Dror E. Warschawski Karine Moncoq Manuela Zoonens Bruno Miroux

Production of biological molecules is a challenge for the next decade in the field of medicinal chemistry. After heterologous production, the biological molecule must be active, well defined homogenous and the cost of its production should remain low. An interesting example is given by the relative success of therapeutic antibodies. Twenty monoclonal therapeutic antibodies are presently on the ...

Journal: :Processes 2022

The derivation of minimal bioreaction models is primary importance to develop monitoring and control strategies cell/microorganism culture production. These can be obtained based on the selection a basis elementary flux modes (EFMs) using an algorithm starting from relatively large set EFMs progressively reducing their numbers geometric least-squares residual criteria. reaction rates associated...

Journal: :E3S web of conferences 2021

Chromium is one of main pollution in sea water, and the establishment detecting kit research hot topic. In this study, immunized mice were obtained by immunogen Cr 3+ -EDTA-BSA, hybridoma strains that secrete -EDTA monoclonal antibody selected. mAb prepared with vivo method. Then, Cr-kit for measurement chromium was developed, its application executed water seafood. Two A321 A424 screened. The ...

Journal: :Proceedings of the National Academy of Sciences 1979

آخوندی, محمد مهدی, بیات, علی احمد, ترک آبادی, ابراهیم, جدی تهرانی, محمود, حیدری, مهناز, دیزجی, عبدالخالق, شکری, فاضل, صادقی, محمد رضا, قدس, رویا,

Introduction: As monoclonal antibodies are potential tools for characterization of soluble or cellular surface antigens, use of these proteins has always been considered in infertility and reproduction research. Therefore, in this study, monoclonal antibodies against human sperm surface antigens were produced. Material and Methods: To produce specific clones against human sperm surface antig...

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