gc-fid and hplc-dad were developed for determination of menadione (mn) and menadione sodium bisulphite (msb). by means of each method, quantitative analysis of msb in commercial pharmaceutical was performed in both direct analysis of msb and analysis of mn by converting msb to mn with sodium carbonate. gc-fid method was carried out on the hp-5 capillary column using nitrogen gas. hplc-dad metho...

an agar well diffusion bioassay method for determination of clarithromycin in human plasma, using micrococcus luteus atcc 9341 as the assay organism, was compared with a selective high-performance liquid chromatographic (hplc) method with uv detection. spiked plasma was used to prepare standard and control samples for both methods. the results of the bioassay analyses with spiked plasma samples...

Background Current analytical methods for characterizing pharmacokinetic and metabolic properties of positron emission tomography (PET) and single photon emission computed tomography (SPECT) probes are limited. Alternative methods to study tracer metabolism are needed. The study objective was to assess the potential of high performance liquid chromatography - inductively coupled plasma - mass s...