Abstract Experiments were conducted to test the hypothesis that interaction of a carbonatitic magma with quartz-rich rocks plays key role in shaping carbonatite complexes. The host represented by quartz, and was synthetic mixtures CaCO3, MgCO3, Na2CO3. With increasing distance from reaction between carbonate liquid quartz produced domain Na(Ca)-rich silicate glass, metasomatic wollastonite, dio...

Original scientific paper Rock burst is a common serious geological hazard in underground engineering, which seriously affects the progress of projects. The mechanism of rock burst can be explained by the distribution law of rock fragments and its fractal characteristics. A simulation experiment of rock burst was conducted with the granite samples under a biaxial loading machine system to analy...

In prion diseases, synapse dysfunction, axon retraction and loss of neuronal polarity precede neuronal death. The mechanisms driving such polarization defects, however, remain unclear. Here, we examined the contribution of RhoA-associated coiled-coil containing kinases (ROCK), key players in neuritogenesis, to prion diseases. We found that overactivation of ROCK signaling occurred in neuronal s...

1 Department of Endocrinology and Internal Medicine, University of Arkansas for Medical Sciences, Little Rock, AR, USA, 2 GIM Foundation, Little Rock, AR, USA, 3 Department of Internal Medicine and Hospital Medicine, Christus Trinity Mother Frances Hospital, Tyler, TX, USA, 4 Department of Policy, University of Arkansas for Little Rock, Little Rock, AR, USA, 5 Tutwiler Clinic, Tutwiler, MS, USA...

This paper deals with the statistical analysis of the uniaxial compressive strength and of the elastic modulus of jointed rock masses under different confining pressures. Properties of the rock masses with different joint fabric, with and without gouge have been considered in the analysis. A large amount of experimental data of jointed rock masses from the literature has been compiled and used ...

This study is part of numerical simulations performed on an in situ heating test conducted by the French National Radioactive Waste Management Agency (Andra) at Meuse/Haute-Marne Underground Research Laboratory (URL) to thermal-hydromechanical behavior host Callovo-Oxfordian COx claystone quasi real conditions, through international research project DECOVALEX. The emphasis put pore pressure inc...

Background: Negative regulatory mechanisms of ROCK signaling are poorly understood. We have discovered a novel mechanism to attenuate ROCK signaling. Results: Coronin1B is a novel binding partner of ROCK2 that inhibits ROCK signaling to myosin. Conclusion: Coronin1B regulates ROCK by a novel signal attenuation mechanism. Significance: Coronin1B attenuation of ROCK signaling is associated with N...

Rock bolts have been widely used as rock reinforcing members in underground coal mine roadways and tunnels. Failures of rock bolts occur as a result of overloading, corrosion, seismic burst and bad grouting, leading to catastrophic economic and personnel losses. Monitoring the health condition of the rock bolts plays an important role in ensuring the safe operation of underground mines. This wo...

[1] Experimental data for alteration of synthetic Martian basalts at pH = 0–1 indicate that chemical fractionations at low pH are vastly different from those observed during terrestrial weathering. Rock surface analyses from Gusev crater are well described by the relationships apparent from low-pH experimental alteration data. A model for rock surface alteration is developed, which indicates th...