BACKGROUND Regional citrate hemodialysis anticoagulation is used when heparin is contraindicated, but most protocols require large infusions of calcium and frequent intradialytic plasma ionized calcium measurements. OBJECTIVES The objective of this study was to determine the safety, efficacy, and effect on calcium balance of regional citrate anticoagulation using sparse plasma ionized calcium...

INTRODUCTION Hutchinson-Gilford progeria syndrome is a rare genetic disorder. It is reported to be present in one in eight million and is characterized by severe growth failure, early loss of hair, lipodystrophy, scleroderma, decreased joint mobility, osteolysis, early atherosclerosis and facial features that resemble those of an aged person. Apart from diabetes mellitus, there are no reported ...

BACKGROUND Fibroblast growth factor -23 (FGF-23) is a key regulator of mineral metabolism. It regulates renal phosphate (Pi) reabsorption and calcitriol synthesis, and has an inhibitory effect on parathyroid hormone (PTH) secretion. FGF-23 increases early in chronic kidney disease (CKD), but the regulation of FGF-23 in mild -to -moderate renal dysfunction is not fully understood. METHODS Nine...

The response to an oral calcium load test was assessed in 17 hypercalciuric nephrolithiasis patients who presented elevated parathyroid hormone (PTH) irrespective of the ionized calcium (sCa2+) levels. Blood samples were collected at baseline (0 min) and at 60 and 180 min after 1 g calcium load for serum PTH, total calcium, sCa2+, and 1.25(OH)2D3 determinations. According to the sCa2+ level at ...

abstract background: to determine daily calcium, vitamin d intake and serum biochemical findings of rickets in adolescent girls. methods: a total of 414 healthy adolescent student girls aged 11-15 years were evaluated from various areas of tehran, iran with different socioeconomic status. a randomized, cross-sectional, prospective and descriptive study was undertaken for calculation of daily ca...

Background: Patients with beta-thalassemia present with severe anemia requiring regular red blood cell transfusions. This can lead to iron overload and its related complications including disorders of the endocrine systems. The aim of this work was to study parathyroid function in children with beta-thalassemia major in correlation with iron load. Methods: 60 patients with beta-thalassemia majo...

Changes in blood concentrations of ionized calcium and total calcium were measured in broiler breeder hens (42 wk old) relative to egg cycle and environmental temperatures. Two environmental temperature treatments were used: 1) temperature cycled daily from a low of 10 C at 0300 h to a high of 25 C at 1600 h; and 2) temperature cycled from a low of 21 C at 0300 h to a high of to a high of 39 C ...

Maintenance of normal blood levels of ionized calcium (Ca2+) plays an important role in the management of the critically ill patient. Therefore, Ca2+ should be collected properly and measured reliably. The sound analytical performance of today's Ca2+ analyzers using ion-selective electrode technology have made measurements accurate and precise. The introduction of this technology allows rapid a...

Investigations of the effects of calcitriol on the inverse sigmoidal relationship between parathyroid hormone (PTH) and ionized calcium (iCa) have yielded contradictory conclusions, possibly because of variations in experimental and analytical approaches. To clarify the existing literature, PTH-iCa curves were constructed by inducing hypo- and hypercalcemia through alterations in dialysate calc...