Aim. To follow the distribution and evolution of macaques genus-specific Alu repeat AluMacYa3 in Cercopithecidae MGMT gene orthologs. Methods. The homology between nucleotide sequences has been determined by BLAST 2.6.1 program. results search identification MGE have obtained CENSOR Results. It shown on example orthologs that is present not only intron macaques, but also other representatives O...

background: members of the vannellidae family are free-living amoebae (fla) distributed mainly in water and soil sources. the present study reports the first isolation of this genus in the biofilm source from hospital environment in tehran, iran. methods: biofilm samples were collected from hospital environment. cultivation was performed in non-nutrient agar covered with a heat-killed escherich...

RhoGEFs play an important role in various signaling cascades and are implicated in human conditions like cancer and mental retardation. A database search combined with screening of a human neuronal teratocarcinoma library identified two novel RhoGEFs, ARHGEF3 and ARHGEF4 (HGMW-approved symbols). The widely expressed ARHGEF3 transcript of 3561 nucleotides encodes a polypeptide of 526 amino acids...

The novel introduction of spaced seed idea in the filtration stage of sequence comparison by Ma et al. (Bioinformatics 18 (2002) 440) has greatly increased the sensitivity of homology search without compromising the speed of search. Finding the optimal spaced seeds is of great importance both theoretically and in designing better search tool for sequence comparison. In this paper, we study the ...

Homologous recombination plays a key role in generating genetic diversity, while maintaining protein functionality. The mechanisms by which RecA enables a single-stranded segment of DNA to recognize a homologous tract within a whole genome are poorly understood. The scale by which homology recognition takes place is of a few tens of base pairs, after which the quest for homology is over. To stu...

The invertible deoxyribonucleic acid (DNA) segment cloned from Salmonella sp. was radioactively labeled and used as a probe to search for homologous sequences by Southern hybridization. Only one copy of the invertible segment could be found on the Salmonella sp. genome. Partial sequence homology with the invertible region was detected in bacteriophage Mu and P1 DNA by low-stringency hybridizati...

DDBJ/EMBL/GenBank International Nucleotide Sequence Database is still increasing, keeping doubling time only slightly longer than one year for the last these years. This situation affects the increase of DDBJ Amino acid sequence Database (DAD) [4], which is made from translation of nucleotide sequences in CDS regions annotated in DDBJ [3], and makes computation time for homology search of DAD l...