نتایج جستجو برای: hodgkin disease
تعداد نتایج: 1503406 فیلتر نتایج به سال:
Abstract Hodgkin lymphoma (HL) is primarily a nodal disease. Cutaneous involvement of HL as presenting feature extremely rare. Skin usually seen metachronous in the course disease and associated with poor prognosis. Primary skin soft tissue can be construed nonhematological, inflammatory, or infective etiology. We report 14-year-old girl fever, weight loss, lymphadenopathy, multiple papular les...
Tissue inhibitor of metalloproteinases (TIMP)-1 and TIMP-2 are proteins with proteinase-inhibiting and cytokine properties. TIMP-1 is active primarily in B cells and B-cell lymphomas, whereas TIMP-2 expression is restricted to T cells. The expression of TIMP-1 and TIMP-2 in lymph nodes from patients with Hodgkin disease (HD) and in Hodgkin-derived cell lines was investigated. In situ hybridizat...
BACKGROUND Hodgkin's lymphoma is characterized by the presence of mono-nucleated Hodgkin cells and bi- to multi-nucleated Reed-Sternberg cells. We have recently shown telomere dysfunction and aberrant synchronous/asynchronous cell divisions during the transition of Hodgkin cells to Reed-Sternberg cells.1 DESIGN AND METHODS To determine whether overall changes in nuclear architecture affect ge...
In the present study, we report on the full range of physical diseases acquired by survivors of Hodgkin lymphoma diagnosed in adolescence or young adulthood. In a Danish nationwide population-based cohort study, 1,768 five-year survivors of Hodgkin lymphoma diagnosed at ages 15-39 years during 1943-2004 and 228,447 comparison subjects matched to survivors on age and year of birth were included....
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