OBJECTIVES To evaluate the associations in twins between within pair differences in birth weight and subsequent blood pressures as adults thereby removing the impact of potential parental confounding variables. DESIGN Historical cohort study. SETTING St Thomas's UK adult twin register, June 1992 to September 1995. PARTICIPANTS 492 pairs of female twins (mean age 54 years). MAIN OUTCOME ...

A historical cohort study of the printing industry was established after an anecdotal report of a cluster of cases of bladder cancer in a newspaper factory in Manchester. The cohort comprised some 9500 men who were members of one or other of two trade unions (the NGA and NATSOPA) in the Manchester area between 1949 and 1963. During the follow up period (1949-83) 3482 deaths occurred among men b...

Objective—To establish which factors predict attendance at a hospital diabetes clinic and for diabetes review in general practice. Design—A historical cohort study of individuals with diabetes identified from general practice records. Information on service contacts and other clinical, social, and demographic variables was collected from general practice records and postal questionnaires. Setti...

OBJECTIVES To investigate the mortality of workers who had been exposed to asbestos, machining fluids and foundry work in a foundry and heavy engineering plant in the railway rolling stock manufacturing industry in New Zealand. METHODS Historical cohort study design. RESULTS For the total workforce of 3522 men employed between 1945 and 1991, follow up was 90% of person-years to 31 December ...

OBJECTIVE To determine the rate and risk of suicide and accidental fatal drug overdose (ie, overdose deemed not to have been suicide) in individuals who had been medically ascertained as having been sexually abused during childhood. DESIGN A historical cohort linkage study of suicide and accidental drug-induced death among victims of child sexual abuse (CSA). SETTING AND PATIENTS Forensic m...

OBJECTIVES Measles was endemic in England during the early 1800s; however, it did not arrive in Australia until 1850 whereas other infectious diseases were known to have arrived much earlier-many with the First Fleet in 1788-leading to the question of why there was a difference. DESIGN Ships surgeons' logbooks from historical archives, 1829-1882, were retrospectively reviewed for measles outb...

OBJECTIVE To determine the relative importance of environmental and genetic effects in the development of rheumatoid arthritis. DESIGN Historical cohort study with record linkage between a twin registry and the Danish discharge registry as well as the Danish national registry of deaths used to estimate completeness. SETTING Two population based nationwide twin birth cohorts. PARTICIPANTS ...

OBJECTIVE To describe the factors associated with nonadherence to TB chemoprophylaxis in patients older than 15 years of age treated via referral TB control programs. METHODS A historical cohort study was carried out based on medical charts related to cases treated via referral TB control programs in the city of Vitória, Brazil, between 2002 and 2007. Cases of infection with Mycobacterium tub...

An historical cohort study was conducted to investigate the rate and extent of neurological recovery in obstetric brachial plexus injury (OBPI) and to identify possible prognostic factors in a cohort of children with OBPI from birth to 7 years. All children (n=56; 31 females, 25 males) with OBPI were evaluated at fixed time intervals by one examiner. They underwent a final neurological examinat...