the rapid advancement of nanotechnology enables us to use nanoscale particles. this material in terms of physical, chemical and biological characteristics are unique compared to larger particles. increased cell division, apoptosis, oxidative stress has been associated with toxic effects of nano-silver. the aim of this study was to evaluate histipotological changes and enzyme activity in nanopar...

Background Cystic fibrosis (CF) is the most prevalent lethal chronic genetic and multivariate disease, widespread in Iranian population. The aim of this study was to evaluate the condition of patients with CF from various dimensions in the last decades in Iran.<b...

Recently, idiopathic pulmonary fibrosis (IPF) associated with hypothyroidism was proposed as a possible link showing worse prognosis than IPF. We have reviewed our archives of interstitial pneumonias (IPs) and examined pathologic and clinical features of IPs associated with hypothyroidism to understand its variations. Pathologically, two cases showed usual interstitial pneumonia pattern, and on...

Adenoid cystic carcinoma (ACC) is a generally slow-growing but highly malignant salivary gland neoplasm with remarkable capacities for local invasion and lung metastasis. The precise characteristics of ACC are not fully understood because there was no suitable animal model. We have successfully established a new human tumor line (ACCI) derived from ACC of the oral floor, which showed a cribrifo...

The clinicopathological features of 29 patients with nodular sclerosing Hodgkin's disease are described. The histological appearances are those of a nodular pattern due to thick fibrous bands which encircle areas of abnormal lymphoid tissue in which a particular form of abnormal reticulum cell can be recognized. They can be further subdivided into well differentiated and poorly differentiated t...