although breast tuberculosis still remains rare, but in endemic countries should be in differential diagnosis of breast cancer and abscess. imaging modalities cannot distinguish between cancer and tuberculosis. acid fast bacilli stain; culture and pcr are helpful diagnostic methods but unfortunately are not very sensitive. negative results do not rule out this diagnosis, so it seems definite di...

DH: dermatitis herpetiformis DIF: direct immunofluorescence INTRODUCTION Dermatitis herpetiformis (DH) is an autoimmune, subepidermal blistering disease associated with gluten sensitivity. It commonly manifests as intensely pruritic papules and vesicles on the extensor surfaces of extremities in a symmetric distribution. Classic histologic findings and data from direct immunofluorescent (DIF) s...

Peribronchiolar metaplasia is a histologic lesion characterized by fibrosis and bronchiolar epithelial proliferation, affecting peribronchiolar alveolar septa and terminal bronchioles. It has been considered a nonspecific tissue reaction secondary to the action of external factors, such as tobacco smoke and microbes, and is a common histologic finding in several diffuse interstitial lung diseas...

This study compared the histologic characteristics of ulcerative colitis with findings on conventional colonoscopy and on magnification and dye application for 70 sites that underwent biopsy. The primary objective was to study the correspondence between histologic findings and endoscopic findings with respect to glandular restructuring and the resolution of inflammation from the active to the r...

Age has been used as a prognostic factor for patients with peripheral neuroblastic tumours (pNTs). The latest analysis disclosed a cut-off around 18 months for the optimal prognostic distinction. The International Neuroblastoma Pathology Classification (INPC) distinguishes favourable and unfavourable histology based on the age-appropriate evaluation of histologic indicators (grade of neuroblast...

Histologic evaluation of neoadjuvant chemotherapy effect is a well-established prognostic indicator in osteosarcoma and Ewing sarcoma arising in bone. Although tumor necrosis is a primary histologic response for the treatment, secondary degenerative changes following necrosis are frequently shown in those tumors. We reviewed some cases of Ewing sarcoma and osteosarcoma of bone with variable his...

OBJECTIVE To evaluate the incidence of unexpected histologic findings in routine tonsillectomy and adenoidectomy specimens. METHODS A retrospective medical record review was performed at a tertiary care children's hospital. The pathology records of 2062 children who underwent tonsil or adenoid surgery were analyzed and the final histologic diagnosis was recorded. RESULTS Four unexpected his...

A 48-year-old man was admitted for evaluation of abnormal shadows on chest radiograph. Chest computed tomography (CT) showed cysts, nodules, and cervical and axillary lymphadenopathies. Elevated serum levels of IgG4 and interleukin (IL)-6 suggested IgG4-related disease (IgG4-RD) or multicentric Castleman's disease (MCD). Histologic findings of the cervical lymph node and right lung S6 biopsies ...

ABSTRACT Degradation of bovine small intestine and respective effects on biomechanics have not been described to date. Biomechanical testing intestinal tissues is often carried out within a few hours donor death tissue deterioration accounted for. Freezing efficient for the preservation several tissues; however, it may cause cellular damage. This study investigated morphologic biomechanical cha...

Dermatitis herpetiformis (DH) emerges as a chronic, immune-mediated, systemic skin pathology closely linked to celiac disease (CD). Characterized by polymorphous and pruritic cutaneous manifestations, DH presents unique clinical diagnostic challenge. In this article, we seek comprehensively delineate the clinical, histologic, immunologic dimensions of DH, with particular emphasis on its etiopat...