To the Editor: Streptococcus suis is a major bacterial pathogen in swine worldwide. Historically, cases in humans have occurred sporadically , mostly in Asia (1,2). However, an outbreak in China involved 215 human cases and 39 deaths (3). Only 3 human cases of S. suis disease were documented in the United States before 2011: 2 domestically acquired cases in New York and Hawaii, and 1 case in a ...

rhythms (for example, by temporary transcutaneous pacing, magnet). • The often-given recommendation of application of the 'current in a fashion that it will not cross the generator ⁄ lead ⁄ chest system' might be of less relevance than currently thought. In our case, repositioning the return electrode away from the apex of the heart did not result in any change of the current necessary to trans...

Label-free detection of the interaction between hexahistidine-tagged human κ-opioid receptor membrane protein and anti-His antibody is demonstrated in liquid by an optical microelectromechanical system utilizing electromagnetically actuated microresonators. Shift in resonance frequency due to accretion of mass on the sensitive surface of microresonators is monitored via an integrated optical re...

Identification of trigger factors is helpful in the diagnosis and management of migraine. Common triggers of migraine are well established but 'hair wash or head bath' as a trigger for migraine has so far not been reported. This prospective study analysed this unusual trigger link in 94 out of 1500 Indian patients who fulfilled the International Headache Society criteria for migraine. In 11 pat...

During the past few decades, much controversy has surrounded the pathophysiology of migraine. Cortical spreading depression (CSD) is widely accepted as the neuronal process underlying visual auras. It has been proposed that CSD can also cause the headaches, at least in migraine with aura. We describe three patients, each fulfilling the International Headache Society criteria for migraine with a...

In September 2011, a 55 year old active man, ex-smoker with previous history of squamous cell cancer of the lung, presented to the hospital with frontal headache of > 12 hours duration and low grade fever. Headache was severe and not accompanied by nausea, vomiting or sensitivity to light. His lung cancer was treated with surgery and radiation therapy, which was completed in 2010. His treatment...

We evaluate the ability of hexahistidine (His6) tags on peptide and protein substrates to recruit deoxyribozymes for modifying those substrates. For two different deoxyribozymes, one that creates tyrosine-RNA nucleopeptides and another that phosphorylates tyrosine side chains, we find substantial improvements in yield, kobs, and Km for peptide substrates due to recruiting by His6/Cu(2+). Howeve...

Copyright © 2007 Massachusetts Medical Society. A 62-year-old man has sudden weakness of the left arm and leg and slurred speech. Except for untreated hypertension, his medical history is unremarkable. He is a current smoker with a smoking history of 45 pack-years. On arrival at the emergency department 1 hour 15 minutes after the onset of symptoms, he reports no headache or vomiting. His blood...

Cervicogenic headache (CEH) is a secondary headache which affects 1.0-4.6 % of the population. Although the costs are unknown, the health consequences are substantial for the individual; especially considering that they often suffers chronicity. Pharmacological management has no or only minor effect on CEH. Thus, we aim to assess the efficacy of chiropractic spinal manipulative therapy (CSMT) f...