BACKGROUND Previous studies on intake of linoleic acid (LA), the predominant n-6 fatty acid, and coronary heart disease (CHD) risk have generated inconsistent results. We performed a systematic review and meta-analysis of prospective cohort studies to summarize the evidence regarding the relation of dietary LA intake and CHD risk. METHODS AND RESULTS We searched MEDLINE and EMBASE databases t...

Intake of dietary factors that serve as methyl group donors may influence promoter hypermethylation in colorectal carcinogenesis. We investigated whether dietary folate, vitamin B2 and vitamin B6, methionine and alcohol were associated with mutL homologue 1 (MLH1) hypermethylation and the related molecular phenotypes of MLH1 protein expression, microsatellite instability (MSI) and BRAF mutation...

BACKGROUND This study describes epidemiological data of non-Hodgkin's lymphoma (NHL) diagnosed from 2001 to 2008 among Saudi men. MATERIALS AND METHODS Retrospective data from all NHL cancer cases among Saudi men recorded in the Saudi Cancer Registry (SCR) between January 2001 and December 2008 were used. Descriptive statistics, analysis of variance, Poisson regression, and simple linear regr...

OBJECTIVES To assess associations between the launch of the National Dementia Strategy (NDS) and antipsychotic prescribing in long-term residential care (LTC) in England. SETTING AND PARTICIPANTS Retrospective analysis of prescribing patterns in 616 LTC institutions (31 619 residents) following launch of the NDS, using information from electronic medicines management system. PRIMARY AND SEC...

A 56 days grow-out experiment with three protein levels (35, 40 and 45%) and three lipid levels (5, 10 and 15%) was conducted to evaluate the optimum protein and lipid ratio for Oriental River Prawn (Macrobrachium nipponense). Four hundred and five prawns, with mean (± SD) weight of 1.40 ± 0.04 g were distributed in 27 glass aquaria and were fed four times daily. Results showed that interaction...

CONTEXT Consumption of red and processed meat has been associated with colorectal cancer in many but not all epidemiological studies; few studies have examined risk in relation to long-term meat intake or the association of meat with rectal cancer. OBJECTIVE To examine the relationship between recent and long-term meat consumption and the risk of incident colon and rectal cancer. DESIGN, SE...

BACKGROUND A number of epidemiological studies have examined the effect of meat consumption on depression. However, no conclusion has been reached. The aim of this study was to examine the relationship between meat consumption and depression. METHODS The electronic databases of PUBMED and EMBASE were searched up to March 2017, for observational studies that examined the relationship between m...

BACKGROUND Studies conducted in Asian populations have suggested that high consumption of soy-based foods that are rich in isoflavone phytoestrogens is associated with a reduced risk of breast cancer. However, the potential associations of other dietary phytoestrogens--i.e., the lignans or their bioactive metabolites, the enterolignans--with the risk of breast cancer are unclear. METHODS We p...