A 56-year-old woman presented with long-standing pain in both knees. She had been suffering from Raynaud’s phenomenon for 10 years. A physical examination showed hard subcutaneous nodules on the extensor surfaces of both knees and elbows (Picture 1: left elbow and right knee) with sclerodactyly and telangieclagia in both hands. The Creactive protein level was normal (0.08 mg/dL, normal < 0.3), ...

Introduction: Association between plasma high-sensitivity C-reactive protein (CRP) concentrations and cardiovascular disease has been Investigated. C-reactive protein (CRP) is an acute phase reactant which is a marker of inflammation in the body. CRP is made by the liver in response to inflammatory cytokines such as interleukin-6 (IL-6) and tumor necrosis factor-&alpha; (TNF&alpha;). Adipose ti...

methods in this study, 150 children diagnosed with liver disease and ascites upon admission to nemazee teaching hospital (shiraz, iran) were examined. patients were divided into spontaneous bacterial peritonitis and sterile ascetic fluid groups according to the pmn count ≥ 250/mm3 in the ascetic fluids. routine laboratory tests were conducted and quantitative c-reactive protein (crp) levels wer...

Background: Preeclampsia is most common medical disordersduring pregnancy, and the rate of hypertension ranges from 5 – 8 % f or all types of pregnancy. There was a significant difference between cancer antigen -125, plasma fibrinogen and Creactive protein to the severity of preeclampsia. Objective: To determine the level ofserum CA-125 level, C-reactive protein and plasma fibrinogen in preecla...

We report 36 cases of spinal tuberculosis who were evaluated at the Internal Medicine Department of Istanbul University between January 1990 and March 2016. Twelve cases were accompanied by active pulmonary tuberculosis while ten patients had a previous history of tuberculosis. Eight patients had diabetes mellitus; six patients were on chronic steroid treatment with a mean dose of 24 mg/day whi...

objectives the overall goal of this study was to carry out a set of comparative analyses of arsr gene in plasmid r773 and bacterial chromosome from escherichia coli bl-21(de3). methods pdb and ncbi databases and chimera, mega4, clc main workbench software and 3d-jigsaw and embl-ebi servers were applied to perform this study. by using these software and servers, multiple analyses including deter...

METHODS Patients Pleural fluids from 374 patients meeting standard criteria for pleural infection were analysed. Patients were recruited in 52 UK centres between 1999 and 2008 (including mycoplasma peak periods), as part of previous randomized trials of intrapleural therapy in pleural infection. Inclusion criteria were clinical evidence of infection and pleural fluid that was macroscopically pu...

Objective: To investigate the effect of hyperbaric oxygen intervention on chronic wound healing in type 2 diabetes mellitus, and its influence on serum inflammatory factors, oxidative stress factors and angiogenesis related factors. Methods: Totally 78 type 2 diabetes mellitus patients with chronic wounds treated in our hospital were randomly divided into 2 groups, 39 cases in each group. The c...

Methotrexate (MTX) is a commonly used disease modifying antirheumatic drug (DMARD) for the treatment of RA because of its affordability, long-term efficacy and acceptable toxicity profile. MTX is also frequently used in the treatment of other forms of inflammatory arthritis. Although MTX is considered to be a well-tolerated DMARD, there is a significant inter-patient variability in the toxicity...