High levels of airborne manganese can be neurotoxic, yet little is known about absorption of this metal via the lungs. Intestinal manganese uptake is upregulated by iron deficiency and is thought to be mediated by divalent metal transporter 1 (DMT1), an iron-regulated factor known to play a role in dietary iron absorption. To better characterize metal absorption from the lungs to the blood and ...

The effect of substrate manganese on tissue manganese levels and activity of the indoleacetic acid (IAA)-oxidase system of cotton (Gossypium hirsutum, L.) was investigated. A sand culture technique was used with 1, 3, 9, 27 and 81 mg manganese (MnSO(4)) per liter nutrient solution applied in various experiments.The following relationships held for both long-term (126 days) and short-term (12-14...

Staphylococcus aureus is a devastating mammalian pathogen for which the development of new therapeutic approaches is urgently needed due to the prevalence of antibiotic resistance. During infection pathogens must overcome the dual threats of host-imposed manganese starvation, termed nutritional immunity, and the oxidative burst of immune cells. These defenses function synergistically, as host-i...

Manganese chloride (50-800 micrograms) was injected unilaterally into the right nostril of rats and its accumulation in the central nervous system (CNS) was monitored. Brain manganese levels were elevated in a dose-dependent, time-dependent, and tissue-dependent manner. Elevated levels of manganese were detected in the right olfactory bulb and olfactory tubercle within 12 hr after instillation ...

A pot experiment was conducted based on a factorial study and complete random block design with three replicates to investigate the phytoremediation potential of Sorghum biocilor L. in soils polluted with nickel and manganese during 2017-2018. The first factor was nickel nitrate (0, 60, and 120 mg kg-1 soil) and the second factor comprised of manganese sulphate (0, 50, and 100 µM). The characte...

Batch experiments were conducted to evaluate the ability of steel slag in removing manganese from aqueous solution. Several variables had been setup to evaluate the performance of steel slag to remove manganese from aqueous solution in different experimental condition. The variables include contact time, size, dosage, pH and initial concentration of manganese. The equilibrium contact time was a...

Superoxide dismutase from the thermophilic anoxygenic photosynthetic bacterium Chloroflexus aurantiacus was cloned, purified, and characterized. This protein is in the manganese- and iron-containing family of superoxide dismutases and is able to use both manganese and iron catalytically. This appears to be the only soluble superoxide dismutase in C. aurantiacus. Iron and manganese cofactors wer...

Prion diseases are fatal neurodegenerative diseases resulting from misfolding of normal cellular prion (PrP(C)) into an abnormal form of scrapie prion (PrP(Sc)). The cellular mechanisms underlying the misfolding of PrP(C) are not well understood. Since cellular prion proteins harbor divalent metal-binding sites in the N-terminal region, we examined the effect of manganese on PrP(C) processing i...

High turnover enantioselective alkene cis-dihydroxylation is achieved with H(2)O(2) catalysed by manganese based complexes containing chiral carboxylato ligands.