The results presented in this paper were motivated by a study of certain patterns, known as restriction sites, in DNA sequences. DNA sequences can be thought of as finite words over a four-letter alphabet {A, T, G, C}, and restriction sites are (sequence-specific) locations of positions in double-stranded DNA where it is cut by a protein known as a restriction enzyme. See Watson (1977). For exa...

This present case report describes two siblings with severe type V hyperlipoproteinaemia, diagnosed very early in life and due to the combination of the common apolipoprotein (Apo) E2 allele and rare mutant variant of ApoE, ApoE3 (Arg 136-->Ser). Phenotyping of ApoE falsely identified E2/E2 phenotype. The presence of mutated ApoE was suspected on an unusual restriction polymorphism of a Hha 1 r...

introduction: the respiratory system is both a route of entry and exit for toxins and injurious agents, as well as being a target for chemical substances and pathogens. therefore, an understanding of the structure and function of the migratory cell populations of pulmonary tissues including alveolar macrophages is central in a number of important disease processes. this study aimed to identify ...

Post-acute care (PAC) services can include home healthcare, long-term hospitals, and skilled nursing facilities. We sought to define factors associated with PAC discharge disposition among Medicare beneficiaries who underwent hepatectomy for hepatocellular carcinoma (HCC). Data a diagnosis of HCC between 2004 2015 were retrieved from the SEER-Medicare database. Discharge was defined as routine ...

Increasing medical costs justify themselves by the success of science in assuring greater longevity. We are all aware range socio-economic problems this longer lifespan causes. This paper intends to address a more latent, concomitant strain on legal system. A few years ago problem manifested itself Supreme Court Appeal, but passed virtually unnoticed. It is ironic that instance, is, Saayman cas...

Parvovirus B19 is a small single-stranded DNA virus, generally causing an asymptomatic infection in 25–50% of the general population. Seropositivity increases with age (15% preschool children, 50% young adults and 85% elderly), transmission most commonly horizontally by respiratory secretions, but also vertically from mother to foetus during pregnancy. The clinically relevant cellular receptor ...

Objectives: Cementless hemiarthroplasty is advised because it reduces the risk of morbidity and mortality in older individuals who use cement. For patients with high-risk clinical issues had femoral neck fractures, we assessed effectiveness cementless hemiarthroplasty. Materials Methods: The design this study was a cross sectional conducted DHQ Teaching Hospital Gujranwala. 48 patients, includi...

Toxin-antitoxin (TA) systems are prevalent in many bacterial genomes and have been implicated in biofilm and persister cell formation, but the contribution of individual chromosomally encoded TA systems during bacterial pathogenesis is not well understood. Of the known TA systems encoded by Escherichia coli, only a subset is associated with strains of extraintestinal pathogenic E. coli (ExPEC)....

The idiopathic hypereosinophilic syndrome (IHES) is a rare disorder characterized by unexplained, persistent eosinophilia associated with multiple organ dysfunction due to eosinophilic tissue infiltration. In the absence of karyotypic abnormalities, there is no specific test to detect clonal eosinophilia in IHES. Analysis of X-chromosome inactivation patterns can be used to determine whether pr...