نتایج جستجو برای: heptad repeat

تعداد نتایج: 73750  

Journal: :Molecular cell 2016
Roland Schüller Ignasi Forné Tobias Straub Amelie Schreieck Yves Texier Nilay Shah Tim-Michael Decker Patrick Cramer Axel Imhof Dirk Eick

The carboxy-terminal domain (CTD) of RNA polymerase II (Pol II) consists of heptad repeats with the consensus motif Y1-S2-P3-T4-S5-P6-S7. Dynamic phosphorylation of the CTD coordinates Pol II progression through the transcription cycle. Here, we use genetic and mass spectrometric approaches to directly detect and map phosphosites along the entire CTD. We confirm phosphorylation of CTD residues ...

1998
JAMES D. CHAPPELL ERIK S. BARTON TRENT H. SMITH GEOFFREY S. BAER DAVID T. DUONG MAX L. NIBERT

A requisite step in reovirus infection of the murine intestine is proteolysis of outer-capsid proteins to yield infectious subvirion particles (ISVPs). When converted to ISVPs by intestinal proteases, virions of reovirus strain type 3 Dearing (T3D) lose 90% of their original infectivity due to cleavage of viral attachment protein s1. In an analysis of eight field isolate strains of type 3 reovi...

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